Comparisons of anterior segment biometry between Chinese and Caucasians using anterior segment optical coherence tomography

Christopher Kai Shun Leung, P. M. Palmiero, R. N. Weinreb, H. Li, Z. Sbeity, Syril Dorairaj, D. Leung, S. Liu, J. M. Liebmann, N. Congdon, D. S. Lam, R. Ritch

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Purpose: To compare anterior segment parameters between eyes of Chinese and Caucasians using anterior segment optical coherence tomography and to evaluate the association between these parameters and anterior chamber angle width between the two ethnic groups. Methods: 60 Chinese and 60 Caucasians, 30 with open angles and 30 with narrow angles (defined as Shaffer grade ≤2 in ≥3 quadrants during dark room gonioscopy) in each group, were consecutively enrolled. One eye of each subject was randomly selected for imaging in a completely darkened room. Measurements, including anterior chamber depth (ACD), scleral spur-to-scleral spur distance (anterior chamber width (ACW)), anterior chamber angle width, iris convexity and iris thickness, were compared between the groups. The associations between angle opening distance and biometric measurements were evaluated with univariate and multivariate regression analyses. Results: There were no differences in age, axial length, anterior chamber angle measurements, pupil diameter and iris convexity between Chinese and Caucasians in both open-angle and narrow-angle groups. However, the ACD and ACW were smaller and the iris was thicker in Chinese. In the multivariate analysis, the ACD was the most influential biometric parameter for angle opening distance in both Chinese and Caucasians. After adjusting the effects of axial length, age and sex, ACD and ACW were significantly smaller in Chinese. Conclusions: Chinese eyes had smaller ACD, smaller ACW and greater iris thickness than Caucasians. ACD was the most influential parameter in determining the angle width in both ethnic groups.

Original languageEnglish (US)
Pages (from-to)1184-1189
Number of pages6
JournalBritish Journal of Ophthalmology
Volume94
Issue number9
DOIs
StatePublished - Sep 1 2010
Externally publishedYes

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Biometry
Optical Coherence Tomography
Anterior Chamber
Iris
Ethnic Groups
Multivariate Analysis
Gonioscopy
Pupil

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Comparisons of anterior segment biometry between Chinese and Caucasians using anterior segment optical coherence tomography. / Leung, Christopher Kai Shun; Palmiero, P. M.; Weinreb, R. N.; Li, H.; Sbeity, Z.; Dorairaj, Syril; Leung, D.; Liu, S.; Liebmann, J. M.; Congdon, N.; Lam, D. S.; Ritch, R.

In: British Journal of Ophthalmology, Vol. 94, No. 9, 01.09.2010, p. 1184-1189.

Research output: Contribution to journalArticle

Leung, CKS, Palmiero, PM, Weinreb, RN, Li, H, Sbeity, Z, Dorairaj, S, Leung, D, Liu, S, Liebmann, JM, Congdon, N, Lam, DS & Ritch, R 2010, 'Comparisons of anterior segment biometry between Chinese and Caucasians using anterior segment optical coherence tomography', British Journal of Ophthalmology, vol. 94, no. 9, pp. 1184-1189. https://doi.org/10.1136/bjo.2009.167296
Leung, Christopher Kai Shun ; Palmiero, P. M. ; Weinreb, R. N. ; Li, H. ; Sbeity, Z. ; Dorairaj, Syril ; Leung, D. ; Liu, S. ; Liebmann, J. M. ; Congdon, N. ; Lam, D. S. ; Ritch, R. / Comparisons of anterior segment biometry between Chinese and Caucasians using anterior segment optical coherence tomography. In: British Journal of Ophthalmology. 2010 ; Vol. 94, No. 9. pp. 1184-1189.
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AU - Li, H.

AU - Sbeity, Z.

AU - Dorairaj, Syril

AU - Leung, D.

AU - Liu, S.

AU - Liebmann, J. M.

AU - Congdon, N.

AU - Lam, D. S.

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