Comparison of facet joint activity on99mTC-MDP SPECT/CT with facet joint signal change on MRI with fat suppression

Vance T Lehman, Robert C. Murphy, Louis A. Schenck, Rickey E. Carter, Geoffrey B. Johnson, Amy L. Kotsenas, Jonathan M. Morris, Mark A. Nathan, John T. Wald, Timothy Maus

Research output: Contribution to journalArticle

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Abstract

PURPOSE We compared signal change on magnetic resonance imaging (MRI) with fat suppression and bone scan activity of lumbar facet joints to determine if these two imaging findings are correlated. METHODS We retrospectively identified all patients who underwent imaging of the lumbar spine for pain evaluation using both technetium-99m methylene disphosphonate single-photon emission computed tomography/computed tomography (99mTc-MDP SPECT/CT) and MRI with at least one fat-suppressed T2-or T1-weighted sequence with gadolinium enhancement within a 180-day interval, at our institution between 1 January 2008 and 19 February 2013. Facet joint activity on 99mTc-MDP SPECT/CT and perifacet signal change on MRI were rated as normal or increased. Agreement between the two examination types were determined with the κ and prevalence-adjusted bias-adjusted κ (PABAK) statistics. RESULTS This study included 60 patients (28 male, 47%), with a mean age of 49±19.7 years (range, 12-93 years). The κ value indicated no agreement between99mTc-MDP SPECT/CT and MRI (κ=-0.026; 95% confidence interval: -0.051, 0.000). The PABAK values were fair to high at each spinal level, which suggests that relatively low disease prevalence lowered the κ values. Together, the κ and PABAK values indicate that there is some degree of intermodality agreement, but that it is not consistent. CONCLUSION Overall, facet joint signal change on fat-suppressed MRI did not always correlate with increased99mTc-MDP SPECT/CT activity. MRI and99mTc-MDP SPECT/CT for facet joint evaluation should not be considered interchangeable examinations in clinical practice or research.

Original languageEnglish (US)
Pages (from-to)277-283
Number of pages7
JournalDiagnostic and Interventional Radiology
Volume22
Issue number3
DOIs
StatePublished - May 1 2016

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Zygapophyseal Joint
Fats
Magnetic Resonance Imaging
Technetium Tc 99m Medronate
Technetium
Gadolinium
Single Photon Emission Computed Tomography Computed Tomography
Spine
Confidence Intervals
Bone and Bones
Pain
Research

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Comparison of facet joint activity on99mTC-MDP SPECT/CT with facet joint signal change on MRI with fat suppression. / Lehman, Vance T; Murphy, Robert C.; Schenck, Louis A.; Carter, Rickey E.; Johnson, Geoffrey B.; Kotsenas, Amy L.; Morris, Jonathan M.; Nathan, Mark A.; Wald, John T.; Maus, Timothy.

In: Diagnostic and Interventional Radiology, Vol. 22, No. 3, 01.05.2016, p. 277-283.

Research output: Contribution to journalArticle

Lehman, Vance T ; Murphy, Robert C. ; Schenck, Louis A. ; Carter, Rickey E. ; Johnson, Geoffrey B. ; Kotsenas, Amy L. ; Morris, Jonathan M. ; Nathan, Mark A. ; Wald, John T. ; Maus, Timothy. / Comparison of facet joint activity on99mTC-MDP SPECT/CT with facet joint signal change on MRI with fat suppression. In: Diagnostic and Interventional Radiology. 2016 ; Vol. 22, No. 3. pp. 277-283.
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abstract = "PURPOSE We compared signal change on magnetic resonance imaging (MRI) with fat suppression and bone scan activity of lumbar facet joints to determine if these two imaging findings are correlated. METHODS We retrospectively identified all patients who underwent imaging of the lumbar spine for pain evaluation using both technetium-99m methylene disphosphonate single-photon emission computed tomography/computed tomography (99mTc-MDP SPECT/CT) and MRI with at least one fat-suppressed T2-or T1-weighted sequence with gadolinium enhancement within a 180-day interval, at our institution between 1 January 2008 and 19 February 2013. Facet joint activity on 99mTc-MDP SPECT/CT and perifacet signal change on MRI were rated as normal or increased. Agreement between the two examination types were determined with the κ and prevalence-adjusted bias-adjusted κ (PABAK) statistics. RESULTS This study included 60 patients (28 male, 47{\%}), with a mean age of 49±19.7 years (range, 12-93 years). The κ value indicated no agreement between99mTc-MDP SPECT/CT and MRI (κ=-0.026; 95{\%} confidence interval: -0.051, 0.000). The PABAK values were fair to high at each spinal level, which suggests that relatively low disease prevalence lowered the κ values. Together, the κ and PABAK values indicate that there is some degree of intermodality agreement, but that it is not consistent. CONCLUSION Overall, facet joint signal change on fat-suppressed MRI did not always correlate with increased99mTc-MDP SPECT/CT activity. MRI and99mTc-MDP SPECT/CT for facet joint evaluation should not be considered interchangeable examinations in clinical practice or research.",
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T1 - Comparison of facet joint activity on99mTC-MDP SPECT/CT with facet joint signal change on MRI with fat suppression

AU - Lehman, Vance T

AU - Murphy, Robert C.

AU - Schenck, Louis A.

AU - Carter, Rickey E.

AU - Johnson, Geoffrey B.

AU - Kotsenas, Amy L.

AU - Morris, Jonathan M.

AU - Nathan, Mark A.

AU - Wald, John T.

AU - Maus, Timothy

PY - 2016/5/1

Y1 - 2016/5/1

N2 - PURPOSE We compared signal change on magnetic resonance imaging (MRI) with fat suppression and bone scan activity of lumbar facet joints to determine if these two imaging findings are correlated. METHODS We retrospectively identified all patients who underwent imaging of the lumbar spine for pain evaluation using both technetium-99m methylene disphosphonate single-photon emission computed tomography/computed tomography (99mTc-MDP SPECT/CT) and MRI with at least one fat-suppressed T2-or T1-weighted sequence with gadolinium enhancement within a 180-day interval, at our institution between 1 January 2008 and 19 February 2013. Facet joint activity on 99mTc-MDP SPECT/CT and perifacet signal change on MRI were rated as normal or increased. Agreement between the two examination types were determined with the κ and prevalence-adjusted bias-adjusted κ (PABAK) statistics. RESULTS This study included 60 patients (28 male, 47%), with a mean age of 49±19.7 years (range, 12-93 years). The κ value indicated no agreement between99mTc-MDP SPECT/CT and MRI (κ=-0.026; 95% confidence interval: -0.051, 0.000). The PABAK values were fair to high at each spinal level, which suggests that relatively low disease prevalence lowered the κ values. Together, the κ and PABAK values indicate that there is some degree of intermodality agreement, but that it is not consistent. CONCLUSION Overall, facet joint signal change on fat-suppressed MRI did not always correlate with increased99mTc-MDP SPECT/CT activity. MRI and99mTc-MDP SPECT/CT for facet joint evaluation should not be considered interchangeable examinations in clinical practice or research.

AB - PURPOSE We compared signal change on magnetic resonance imaging (MRI) with fat suppression and bone scan activity of lumbar facet joints to determine if these two imaging findings are correlated. METHODS We retrospectively identified all patients who underwent imaging of the lumbar spine for pain evaluation using both technetium-99m methylene disphosphonate single-photon emission computed tomography/computed tomography (99mTc-MDP SPECT/CT) and MRI with at least one fat-suppressed T2-or T1-weighted sequence with gadolinium enhancement within a 180-day interval, at our institution between 1 January 2008 and 19 February 2013. Facet joint activity on 99mTc-MDP SPECT/CT and perifacet signal change on MRI were rated as normal or increased. Agreement between the two examination types were determined with the κ and prevalence-adjusted bias-adjusted κ (PABAK) statistics. RESULTS This study included 60 patients (28 male, 47%), with a mean age of 49±19.7 years (range, 12-93 years). The κ value indicated no agreement between99mTc-MDP SPECT/CT and MRI (κ=-0.026; 95% confidence interval: -0.051, 0.000). The PABAK values were fair to high at each spinal level, which suggests that relatively low disease prevalence lowered the κ values. Together, the κ and PABAK values indicate that there is some degree of intermodality agreement, but that it is not consistent. CONCLUSION Overall, facet joint signal change on fat-suppressed MRI did not always correlate with increased99mTc-MDP SPECT/CT activity. MRI and99mTc-MDP SPECT/CT for facet joint evaluation should not be considered interchangeable examinations in clinical practice or research.

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