Comparison of endovascular and surgical treatments for intracranial aneurysms: an evidence-based review

Adnan I. Qureshi, Vallabh Janardhan, Ricardo A. Hanel, Giuseppe Lanzino

Research output: Contribution to journalReview article

54 Citations (Scopus)

Abstract

Intracranial aneurysms can be treated with endovascular or surgical techniques. We provide an objective comparison of these treatments, using data from single-centre studies, multicentre studies with and without independent outcome ascertainment, and randomised clinical trials. We compared the outcomes of patients who were candidates for endovascular treatment, surgical treatment, or both. In patients with ruptured intracranial aneurysms, rates of aneurysm obliteration were higher, and need for second treatment was lower, after surgery than after endovascular treatment. However, in observational studies and randomised trials, outcome at discharge, at 2-6 months, and at 1 year, and later survival, were all better after endovascular treatment than after surgery. The results suggest that the higher rates of incomplete obliteration and retreatment after endovascular treatment do not affect patients' clinical outcome. In observational studies of patients with unruptured intracranial aneurysms, discharge outcomes were better and hospital costs were lower after endovascular treatment than after surgery. These patients showed no difference between the two treatments in 1-year outcomes and later rebleeding, although few data were available for this comparison.

Original languageEnglish (US)
Pages (from-to)816-825
Number of pages10
JournalLancet Neurology
Volume6
Issue number9
DOIs
StatePublished - Sep 2007
Externally publishedYes

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Intracranial Aneurysm
Therapeutics
Observational Studies
Ruptured Aneurysm
Retreatment
Hospital Costs
Multicenter Studies
Aneurysm
Randomized Controlled Trials
Survival

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Comparison of endovascular and surgical treatments for intracranial aneurysms : an evidence-based review. / Qureshi, Adnan I.; Janardhan, Vallabh; Hanel, Ricardo A.; Lanzino, Giuseppe.

In: Lancet Neurology, Vol. 6, No. 9, 09.2007, p. 816-825.

Research output: Contribution to journalReview article

Qureshi, Adnan I. ; Janardhan, Vallabh ; Hanel, Ricardo A. ; Lanzino, Giuseppe. / Comparison of endovascular and surgical treatments for intracranial aneurysms : an evidence-based review. In: Lancet Neurology. 2007 ; Vol. 6, No. 9. pp. 816-825.
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