TY - JOUR
T1 - Comparison of endoscopic treatment modalities for Barrett's neoplasia
AU - David, Waseem J.
AU - Qumseya, Bashar J.
AU - Qumsiyeh, Yazen
AU - Heckman, Michael G.
AU - Diehl, Nancy N.
AU - Wallace, Michael B.
AU - Raimondo, Massimo
AU - Woodward, Timothy A.
AU - Wolfsen, Herbert C.
PY - 2015/11/1
Y1 - 2015/11/1
N2 - Background There are few data comparing endoscopic treatment outcomes for Barrett's esophagus (BE). Objective To compare treatment outcomes in BE patients treated with radiofrequency ablation (RFA), RFA after EMR, and porfimer sodium photodynamic therapy (Ps-PDT). Design Retrospective, observational study. Setting Single tertiary center between 2001 and 2013. Patients A total of 342 BE patients treated with RFA (n = 119), EMR+RFA (n = 98), and Ps-PDT (n = 125). Main Outcome Measurements Rates of complete remission of intestinal metaplasia (CRIM), BE recurrence, and adverse events. Results Baseline BE high-grade dysplasia (HGD) and adenocarcinoma were more common in the Ps-PDT group (89%) compared with the EMR-RFA (70%) and RFA (37%) groups. At a median follow-up of 14.2 months, 173 patients (50.6%) achieved CRIM. CRIM was significantly more common in Ps-PDT patients compared with RFA (P
AB - Background There are few data comparing endoscopic treatment outcomes for Barrett's esophagus (BE). Objective To compare treatment outcomes in BE patients treated with radiofrequency ablation (RFA), RFA after EMR, and porfimer sodium photodynamic therapy (Ps-PDT). Design Retrospective, observational study. Setting Single tertiary center between 2001 and 2013. Patients A total of 342 BE patients treated with RFA (n = 119), EMR+RFA (n = 98), and Ps-PDT (n = 125). Main Outcome Measurements Rates of complete remission of intestinal metaplasia (CRIM), BE recurrence, and adverse events. Results Baseline BE high-grade dysplasia (HGD) and adenocarcinoma were more common in the Ps-PDT group (89%) compared with the EMR-RFA (70%) and RFA (37%) groups. At a median follow-up of 14.2 months, 173 patients (50.6%) achieved CRIM. CRIM was significantly more common in Ps-PDT patients compared with RFA (P
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U2 - 10.1016/j.gie.2015.03.1979
DO - 10.1016/j.gie.2015.03.1979
M3 - Article
C2 - 26071064
AN - SCOPUS:84944354293
SN - 0016-5107
VL - 82
SP - 793-803e3
JO - Gastrointestinal Endoscopy
JF - Gastrointestinal Endoscopy
IS - 5
ER -