Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli

Shawn Vasoo, Scott A. Cunningham, Peggy C. Kohner, Patricia J. Simner, Jayawant N. Mandrekar, Karen Lolans, Mary K. Hayden, Robin Patel

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Abstract

We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test-the Carba NP test (CNP)-and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P=0.08), but CNP was more specific (100% versus 80%; P<0.0001) and faster.

Original languageEnglish (US)
Pages (from-to)3097-3101
Number of pages5
JournalJournal of clinical microbiology
Volume51
Issue number9
DOIs
StatePublished - Sep 1 2013

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ASJC Scopus subject areas

  • Microbiology (medical)

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