Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli

Shawn Vasoo; Scott A. Cunningham; Peggy C. Kohner; Patricia J. Simner; Jayawant N. Mandrekar; Karen Lolans; Mary K. Hayden; Robin Patel

doi:10.1128/JCM.00965-13

Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli

Shawn Vasoo, Scott A. Cunningham, Peggy C. Kohner, Patricia J. Simner, Jayawant N. Mandrekar, Karen Lolans, Mary K. Hayden, Robin Patel

Research output: Contribution to journal › Article › peer-review

79 Scopus citations

Abstract

We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test-the Carba NP test (CNP)-and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P=0.08), but CNP was more specific (100% versus 80%; P<0.0001) and faster.

Original language	English (US)
Pages (from-to)	3097-3101
Number of pages	5
Journal	Journal of clinical microbiology
Volume	51
Issue number	9
DOIs	https://doi.org/10.1128/JCM.00965-13
State	Published - Sep 2013

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/JCM.00965-13

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Vasoo, S., Cunningham, S. A., Kohner, P. C., Simner, P. J., Mandrekar, J. N., Lolans, K., Hayden, M. K., & Patel, R. (2013). Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli. Journal of clinical microbiology, 51(9), 3097-3101. https://doi.org/10.1128/JCM.00965-13

Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli. / Vasoo, Shawn; Cunningham, Scott A.; Kohner, Peggy C. et al.
In: Journal of clinical microbiology, Vol. 51, No. 9, 09.2013, p. 3097-3101.

Research output: Contribution to journal › Article › peer-review

Vasoo, S, Cunningham, SA, Kohner, PC, Simner, PJ, Mandrekar, JN, Lolans, K, Hayden, MK & Patel, R 2013, 'Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli', Journal of clinical microbiology, vol. 51, no. 9, pp. 3097-3101. https://doi.org/10.1128/JCM.00965-13

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Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli

Abstract

ASJC Scopus subject areas

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