Comparison of a gel versus solution-based vehicle for the delivery of acetylcholine in QSART

David M. Sletten, Kurt Kimpinski, Stephen D. Weigand, Phillip Anson Low

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Quantitative Sudomotor Axon Reflex Testing is a useful measure of post ganglionic sudomotor function. The test is based on the iontophoresis of an acetylcholine solution which induces a local sweat response. We have previously described a gel-based vehicle that may provide another option for the iontophoresis of acetylcholine. It was our objective to compare the influence of the vehicle (gel versus solution) on sudomotor recordings and perceived discomfort. Results show gel-based vehicles are very similar to solution-based vehicles during Quantitative Sudomotor Axon Reflex Testing.

Original languageEnglish (US)
Pages (from-to)123-126
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
Volume158
Issue number1-2
DOIs
StatePublished - Dec 8 2010

Fingerprint

Acetylcholine
Iontophoresis
Gels
Axons
Reflex
Sweat

Keywords

  • Acetylcholine
  • Gel
  • QSART
  • Solution
  • Sudomotor
  • Vehicle

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Endocrine and Autonomic Systems

Cite this

Comparison of a gel versus solution-based vehicle for the delivery of acetylcholine in QSART. / Sletten, David M.; Kimpinski, Kurt; Weigand, Stephen D.; Low, Phillip Anson.

In: Autonomic Neuroscience: Basic and Clinical, Vol. 158, No. 1-2, 08.12.2010, p. 123-126.

Research output: Contribution to journalArticle

Sletten, David M. ; Kimpinski, Kurt ; Weigand, Stephen D. ; Low, Phillip Anson. / Comparison of a gel versus solution-based vehicle for the delivery of acetylcholine in QSART. In: Autonomic Neuroscience: Basic and Clinical. 2010 ; Vol. 158, No. 1-2. pp. 123-126.
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