Comparison of a gel versus solution-based vehicle for the delivery of acetylcholine in QSART

David M. Sletten, Kurt Kimpinski, Stephen D. Weigand, Phillip A. Low

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Quantitative Sudomotor Axon Reflex Testing is a useful measure of post ganglionic sudomotor function. The test is based on the iontophoresis of an acetylcholine solution which induces a local sweat response. We have previously described a gel-based vehicle that may provide another option for the iontophoresis of acetylcholine. It was our objective to compare the influence of the vehicle (gel versus solution) on sudomotor recordings and perceived discomfort. Results show gel-based vehicles are very similar to solution-based vehicles during Quantitative Sudomotor Axon Reflex Testing.

Original languageEnglish (US)
Pages (from-to)123-126
Number of pages4
JournalAutonomic Neuroscience: Basic and Clinical
Volume158
Issue number1-2
DOIs
StatePublished - Dec 8 2010

Keywords

  • Acetylcholine
  • Gel
  • QSART
  • Solution
  • Sudomotor
  • Vehicle

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Comparison of a gel versus solution-based vehicle for the delivery of acetylcholine in QSART'. Together they form a unique fingerprint.

Cite this