Comparative endoscopic study of primary gastric lymphoma vs. gastric carcinoma

Santhi Swaroop Vege, K. M. Mohandas, V. D. Swaroop, C. S. Soman, S. Krishnamurthi, A. Nagral, P. Jagannath, L. J. Desouza

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The endoscopic records of 56 patients with primary gastric lymphoma and 120 patients with gastric adenocarcinoma (matched for age and sex) were compared with respect to site, extent, and type of tumor by endoscopy and biopsy results. Diagnosis of lymphoma was suspected on the basis of gross endoscopic appearance in 30 patients with 96% sensitivity. The endoscopic findings that achieved statistical significance in favor of lymphoma were extensive disease involving whole stomach, proximal stomach involvement, extension of tumor into duodenum, and the presence of volcano crater-like ulcers on polypoid lesions. Endoscopic biopsies were positive for lymphoma in 92% patients. Immunoperoxidase staining for leucocyte common antigen was positive in all the 24 patients with lymphoma where it was performed. We conclude that lymphoid origin of the stomach tumor may be suspected in one- half of the cases of primary gastric lymphoma by gross endoscopic findings. Multiple endoscopic biopsies are safe and highly sensitive and specific in the diagnosis of primary gastric lymphoma.

Original languageEnglish (US)
Pages (from-to)94-97
Number of pages4
JournalJournal of Surgical Oncology
Volume56
Issue number2
DOIs
StatePublished - 1994
Externally publishedYes

Fingerprint

Stomach
Lymphoma
Carcinoma
Biopsy
CD45 Antigens
Neoplasms
Duodenum
Endoscopy
Ulcer
Adenocarcinoma
Familial primary gastric lymphoma
Staining and Labeling

Keywords

  • biopsy
  • diagnostic
  • etiology
  • gastroscopy
  • neoplasm
  • stomach

ASJC Scopus subject areas

  • Surgery
  • Oncology

Cite this

Vege, S. S., Mohandas, K. M., Swaroop, V. D., Soman, C. S., Krishnamurthi, S., Nagral, A., ... Desouza, L. J. (1994). Comparative endoscopic study of primary gastric lymphoma vs. gastric carcinoma. Journal of Surgical Oncology, 56(2), 94-97. https://doi.org/10.1002/jso.2930560209

Comparative endoscopic study of primary gastric lymphoma vs. gastric carcinoma. / Vege, Santhi Swaroop; Mohandas, K. M.; Swaroop, V. D.; Soman, C. S.; Krishnamurthi, S.; Nagral, A.; Jagannath, P.; Desouza, L. J.

In: Journal of Surgical Oncology, Vol. 56, No. 2, 1994, p. 94-97.

Research output: Contribution to journalArticle

Vege, SS, Mohandas, KM, Swaroop, VD, Soman, CS, Krishnamurthi, S, Nagral, A, Jagannath, P & Desouza, LJ 1994, 'Comparative endoscopic study of primary gastric lymphoma vs. gastric carcinoma', Journal of Surgical Oncology, vol. 56, no. 2, pp. 94-97. https://doi.org/10.1002/jso.2930560209
Vege, Santhi Swaroop ; Mohandas, K. M. ; Swaroop, V. D. ; Soman, C. S. ; Krishnamurthi, S. ; Nagral, A. ; Jagannath, P. ; Desouza, L. J. / Comparative endoscopic study of primary gastric lymphoma vs. gastric carcinoma. In: Journal of Surgical Oncology. 1994 ; Vol. 56, No. 2. pp. 94-97.
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