Combined Vibro-acoustography (VA) imaging and Shearwave Dispersion Ultrasonic Vibrometry (SDUV) for measuring prostate viscoelastic material properties - An in vitro feasibility study

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Improved methods for prostate guided-biopsy are required to effectively guide needle biopsy to the suspected site. In addition, tissue stiffness measurement would help identifying a suspected site to perform biopsy because stiffness has been shown to correlate with pathology. More importantly, early detection of prostate cancer may guide therapy and eliminate invasive procedures. Vibro-acoustography (VA) is sensitive to tissue stiffness and may allow locating an appropriate side for biopsy. Furthermore, Shearwave Dispersion Ultrasound Vibrometry (SDUV) can provide quantitative information about tissue viscoelasticity. For prostate applications, the SDUV technique should be guided by an imaging modality leading to a better biopsy and reduction of the sampling error. The purpose of this study is to evaluate the feasibility of combining VA and SDUV to perform "virtual biopsy" at a specific location. Shear elasticity and viscosity measurements of an excised human prostate are obtained and discussed.

Original languageEnglish (US)
Title of host publication20th International Congress on Acoustics 2010, ICA 2010 - Incorporating Proceedings of the 2010 Annual Conference of the Australian Acoustical Society
Pages4122-4125
Number of pages4
StatePublished - Dec 1 2010
Event20th International Congress on Acoustics 2010, ICA 2010 - Incorporating the 2010 Annual Conference of the Australian Acoustical Society - Sydney, NSW, Australia
Duration: Aug 23 2010Aug 27 2010

Publication series

Name20th International Congress on Acoustics 2010, ICA 2010 - Incorporating Proceedings of the 2010 Annual Conference of the Australian Acoustical Society
Volume5

Other

Other20th International Congress on Acoustics 2010, ICA 2010 - Incorporating the 2010 Annual Conference of the Australian Acoustical Society
CountryAustralia
CitySydney, NSW
Period8/23/108/27/10

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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    Mitri, F. G., Urban, M. W., Fatemi, M., & Greenleaf, J. F. (2010). Combined Vibro-acoustography (VA) imaging and Shearwave Dispersion Ultrasonic Vibrometry (SDUV) for measuring prostate viscoelastic material properties - An in vitro feasibility study. In 20th International Congress on Acoustics 2010, ICA 2010 - Incorporating Proceedings of the 2010 Annual Conference of the Australian Acoustical Society (pp. 4122-4125). (20th International Congress on Acoustics 2010, ICA 2010 - Incorporating Proceedings of the 2010 Annual Conference of the Australian Acoustical Society; Vol. 5).