Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination: Prospective assessment of patient perceptions and preferences

Thomas M. Gluecker, C. Daniel Johnson, William S. Harmsen, Kenneth P. Offord, Ann M. Harris, Lynn A. Wilson, David A. Ahlquist

Research output: Contribution to journalArticle

244 Citations (Scopus)

Abstract

PURPOSE: To prospectively assess and compare perceptions of and preferences for computed tomographic (CT) colonography, colonoscopy, and double-contrast barium enema examination (DCBE) by asymptomatic patients undergoing colorectal cancer screening. MATERIALS AND METHODS: A total of 696 asymptomatic patients at higher-than-average risk undergoing colorectal cancer screening were consecutively recruited to undergo both CT colonography and colonoscopy (group 1), and a like group of 617 patients was separately recruited to undergo both CT colonography and DCBE (group 2). Standard bowel preparations were different between the groups undergoing colonoscopy and DCBE. Each patient completed a questionnaire that assessed preparation inconvenience and discomfort, examination discomfort, willingness to repeat examinations, and examination preference. Survey results were compared for significance by using the Wilcoxon rank sum or X2 test. RESULTS: The majority of patients considered the preparation to be uncomfortable (group 1, 460 of 515 [89%]; group 2, 482 of 538 [90%]) and inconvenient (group 1, 393 of 502 [78%]; group 2, 427 of 527 [81%]). Reported discomfort was similar at CT colonography and colonoscopy (P = .63) but was less at CT colonography than at DCBE (P < .001). Patients experienced significantly less discomfort than expected at both CT colonography and colonoscopy but not at DCBE. Patients' willingness to undergo frequent rescreening was significantly greater for CT colonography than for either colonoscopy or DCBE. The acceptable time interval between screenings was significantly shorter for all examinations if the bowel preparation could be avoided. Overall, patients preferred CT colonography to colonoscopy (group 1, 72.3% vs 5.1%; P < .001) or to DCBE (group 2, 97.0% vs 0.4%; P < .001). CONCLUSION: Patients undergoing colorectal cancer screening prefer CT colonography to both colonoscopy and DCBE. The majority of patients experience discomfort and inconvenience with cathartic bowel preparation.

Original languageEnglish (US)
Pages (from-to)378-384
Number of pages7
JournalRadiology
Volume227
Issue number2
DOIs
StatePublished - May 1 2003

Fingerprint

Computed Tomographic Colonography
Patient Preference
Colonoscopy
Early Detection of Cancer
Colorectal Neoplasms
Barium Enema
Cathartics

Keywords

  • Barium enema examination
  • Cancer screening Colon, CT
  • Colonoscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination : Prospective assessment of patient perceptions and preferences. / Gluecker, Thomas M.; Johnson, C. Daniel; Harmsen, William S.; Offord, Kenneth P.; Harris, Ann M.; Wilson, Lynn A.; Ahlquist, David A.

In: Radiology, Vol. 227, No. 2, 01.05.2003, p. 378-384.

Research output: Contribution to journalArticle

Gluecker, Thomas M. ; Johnson, C. Daniel ; Harmsen, William S. ; Offord, Kenneth P. ; Harris, Ann M. ; Wilson, Lynn A. ; Ahlquist, David A. / Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination : Prospective assessment of patient perceptions and preferences. In: Radiology. 2003 ; Vol. 227, No. 2. pp. 378-384.
@article{599e0c18861a4bbfb68b4a4c8d95054a,
title = "Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination: Prospective assessment of patient perceptions and preferences",
abstract = "PURPOSE: To prospectively assess and compare perceptions of and preferences for computed tomographic (CT) colonography, colonoscopy, and double-contrast barium enema examination (DCBE) by asymptomatic patients undergoing colorectal cancer screening. MATERIALS AND METHODS: A total of 696 asymptomatic patients at higher-than-average risk undergoing colorectal cancer screening were consecutively recruited to undergo both CT colonography and colonoscopy (group 1), and a like group of 617 patients was separately recruited to undergo both CT colonography and DCBE (group 2). Standard bowel preparations were different between the groups undergoing colonoscopy and DCBE. Each patient completed a questionnaire that assessed preparation inconvenience and discomfort, examination discomfort, willingness to repeat examinations, and examination preference. Survey results were compared for significance by using the Wilcoxon rank sum or X2 test. RESULTS: The majority of patients considered the preparation to be uncomfortable (group 1, 460 of 515 [89{\%}]; group 2, 482 of 538 [90{\%}]) and inconvenient (group 1, 393 of 502 [78{\%}]; group 2, 427 of 527 [81{\%}]). Reported discomfort was similar at CT colonography and colonoscopy (P = .63) but was less at CT colonography than at DCBE (P < .001). Patients experienced significantly less discomfort than expected at both CT colonography and colonoscopy but not at DCBE. Patients' willingness to undergo frequent rescreening was significantly greater for CT colonography than for either colonoscopy or DCBE. The acceptable time interval between screenings was significantly shorter for all examinations if the bowel preparation could be avoided. Overall, patients preferred CT colonography to colonoscopy (group 1, 72.3{\%} vs 5.1{\%}; P < .001) or to DCBE (group 2, 97.0{\%} vs 0.4{\%}; P < .001). CONCLUSION: Patients undergoing colorectal cancer screening prefer CT colonography to both colonoscopy and DCBE. The majority of patients experience discomfort and inconvenience with cathartic bowel preparation.",
keywords = "Barium enema examination, Cancer screening Colon, CT, Colonoscopy",
author = "Gluecker, {Thomas M.} and Johnson, {C. Daniel} and Harmsen, {William S.} and Offord, {Kenneth P.} and Harris, {Ann M.} and Wilson, {Lynn A.} and Ahlquist, {David A.}",
year = "2003",
month = "5",
day = "1",
doi = "10.1148/radiol.2272020293",
language = "English (US)",
volume = "227",
pages = "378--384",
journal = "Radiology",
issn = "0033-8419",
publisher = "Radiological Society of North America Inc.",
number = "2",

}

TY - JOUR

T1 - Colorectal cancer screening with CT colonography, colonoscopy, and double-contrast barium enema examination

T2 - Prospective assessment of patient perceptions and preferences

AU - Gluecker, Thomas M.

AU - Johnson, C. Daniel

AU - Harmsen, William S.

AU - Offord, Kenneth P.

AU - Harris, Ann M.

AU - Wilson, Lynn A.

AU - Ahlquist, David A.

PY - 2003/5/1

Y1 - 2003/5/1

N2 - PURPOSE: To prospectively assess and compare perceptions of and preferences for computed tomographic (CT) colonography, colonoscopy, and double-contrast barium enema examination (DCBE) by asymptomatic patients undergoing colorectal cancer screening. MATERIALS AND METHODS: A total of 696 asymptomatic patients at higher-than-average risk undergoing colorectal cancer screening were consecutively recruited to undergo both CT colonography and colonoscopy (group 1), and a like group of 617 patients was separately recruited to undergo both CT colonography and DCBE (group 2). Standard bowel preparations were different between the groups undergoing colonoscopy and DCBE. Each patient completed a questionnaire that assessed preparation inconvenience and discomfort, examination discomfort, willingness to repeat examinations, and examination preference. Survey results were compared for significance by using the Wilcoxon rank sum or X2 test. RESULTS: The majority of patients considered the preparation to be uncomfortable (group 1, 460 of 515 [89%]; group 2, 482 of 538 [90%]) and inconvenient (group 1, 393 of 502 [78%]; group 2, 427 of 527 [81%]). Reported discomfort was similar at CT colonography and colonoscopy (P = .63) but was less at CT colonography than at DCBE (P < .001). Patients experienced significantly less discomfort than expected at both CT colonography and colonoscopy but not at DCBE. Patients' willingness to undergo frequent rescreening was significantly greater for CT colonography than for either colonoscopy or DCBE. The acceptable time interval between screenings was significantly shorter for all examinations if the bowel preparation could be avoided. Overall, patients preferred CT colonography to colonoscopy (group 1, 72.3% vs 5.1%; P < .001) or to DCBE (group 2, 97.0% vs 0.4%; P < .001). CONCLUSION: Patients undergoing colorectal cancer screening prefer CT colonography to both colonoscopy and DCBE. The majority of patients experience discomfort and inconvenience with cathartic bowel preparation.

AB - PURPOSE: To prospectively assess and compare perceptions of and preferences for computed tomographic (CT) colonography, colonoscopy, and double-contrast barium enema examination (DCBE) by asymptomatic patients undergoing colorectal cancer screening. MATERIALS AND METHODS: A total of 696 asymptomatic patients at higher-than-average risk undergoing colorectal cancer screening were consecutively recruited to undergo both CT colonography and colonoscopy (group 1), and a like group of 617 patients was separately recruited to undergo both CT colonography and DCBE (group 2). Standard bowel preparations were different between the groups undergoing colonoscopy and DCBE. Each patient completed a questionnaire that assessed preparation inconvenience and discomfort, examination discomfort, willingness to repeat examinations, and examination preference. Survey results were compared for significance by using the Wilcoxon rank sum or X2 test. RESULTS: The majority of patients considered the preparation to be uncomfortable (group 1, 460 of 515 [89%]; group 2, 482 of 538 [90%]) and inconvenient (group 1, 393 of 502 [78%]; group 2, 427 of 527 [81%]). Reported discomfort was similar at CT colonography and colonoscopy (P = .63) but was less at CT colonography than at DCBE (P < .001). Patients experienced significantly less discomfort than expected at both CT colonography and colonoscopy but not at DCBE. Patients' willingness to undergo frequent rescreening was significantly greater for CT colonography than for either colonoscopy or DCBE. The acceptable time interval between screenings was significantly shorter for all examinations if the bowel preparation could be avoided. Overall, patients preferred CT colonography to colonoscopy (group 1, 72.3% vs 5.1%; P < .001) or to DCBE (group 2, 97.0% vs 0.4%; P < .001). CONCLUSION: Patients undergoing colorectal cancer screening prefer CT colonography to both colonoscopy and DCBE. The majority of patients experience discomfort and inconvenience with cathartic bowel preparation.

KW - Barium enema examination

KW - Cancer screening Colon, CT

KW - Colonoscopy

UR - http://www.scopus.com/inward/record.url?scp=0037408003&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0037408003&partnerID=8YFLogxK

U2 - 10.1148/radiol.2272020293

DO - 10.1148/radiol.2272020293

M3 - Article

C2 - 12732696

AN - SCOPUS:0037408003

VL - 227

SP - 378

EP - 384

JO - Radiology

JF - Radiology

SN - 0033-8419

IS - 2

ER -