Abstract
Globally, more than 1 million new cases of colorectal cancer (CRC) are diagnosed each year and CRC accounts for 10% of all cancer deaths. Symptoms (i.e., hematochezia, melena, change in bowel habits, etc.) and signs (i.e., anemia, positive fecal occult blood test, etc.) of CRC can be subtle and non-specific, but often indicate relatively advanced-stage disease. Since prognosis is inversely associated with CRC stage, early detection of premalignant adenomas or locally-invasive cancers is a clinical priority. Therapy for invasive malignancy is multi-modal and can involve surgery, chemotherapy and radiation therapy. Although not universally applied, guidelines have been developed for post-therapeutic CRC surveillance to detect recurrent and metachronous lesions.
Original language | English (US) |
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Title of host publication | Practical Gastroenterology and Hepatology |
Subtitle of host publication | Small and Large Intestine and Pancreas |
Publisher | Wiley-Blackwell |
Pages | 351-360 |
Number of pages | 10 |
ISBN (Print) | 9781405182744 |
DOIs | |
State | Published - Aug 31 2010 |
Keywords
- Adenocarcinoma
- Adenoma
- Hyperplastic polyp
- Serrated adenoma
- Tubular adenoma
- Tubulovillous adenoma
- Villous adenoma
ASJC Scopus subject areas
- Medicine(all)