Colon cancer, version 3.2014

Al B. Benson, Alan P. Venook, Tanios Bekaii-Saab, Emily Chan, Yi Jen Chen, Harry S. Cooper, Paul F. Engstrom, Peter C. Enzinger, Moon J. Fenton, Charles S. Fuchs, Jean L. Grem, Steven Hunt, Ahmed Kamel, Lucille A. Leong, Edward Lin, Wells Messersmith, Mary F. Mulcahy, James D. Murphy, Steven Nurkin, Eric RohrenDavid P. Ryan, Leonard Saltz, Sunil Sharma, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Elena M. Stoffel, Eden Stotsky-Himelfarb, Christopher G. Willett, Kristina M. Gregory, Deborah A. Freedman-Cass

Research output: Contribution to journalArticle

153 Scopus citations

Abstract

The NCCN Guidelines for Colon Cancer address diagnosis, pathologic staging, surgical management, perioperative treatment, posttreatment surveillance, management of recurrent and metastatic disease,and survivorship. This portion of the guidelines focuses on the use of systemic therapy in metastatic disease. The management of metastatic colorectal cancer involves a continuum of care in which patients are exposed sequentially to a variety of active agents, either in combinations or as single agents. Choice of therapy is based on the goals of treatment, the type and timing of prior therapy, the different efficacy and toxicity profiles of the drugs, the mutational status of the tumor, and patient preference.

Original languageEnglish (US)
Pages (from-to)1028-1059
Number of pages32
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume12
Issue number7
DOIs
StatePublished - Jul 1 2014

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ASJC Scopus subject areas

  • Oncology

Cite this

Benson, A. B., Venook, A. P., Bekaii-Saab, T., Chan, E., Chen, Y. J., Cooper, H. S., Engstrom, P. F., Enzinger, P. C., Fenton, M. J., Fuchs, C. S., Grem, J. L., Hunt, S., Kamel, A., Leong, L. A., Lin, E., Messersmith, W., Mulcahy, M. F., Murphy, J. D., Nurkin, S., ... Freedman-Cass, D. A. (2014). Colon cancer, version 3.2014. JNCCN Journal of the National Comprehensive Cancer Network, 12(7), 1028-1059. https://doi.org/10.6004/jnccn.2014.0099