Cohorts and consortia conference: A summary report (Banff, Canada, June 17-19, 2009)

Paolo Boffetta, Graham A. Colditz, John D. Potter, Laurence Kolonel, Paula J. Robson, Reza Malekzadeh, Daniela Seminara, Ellen L. Goode, Keun Young Yoo, Paul Demers, Richard Gallagher, Ross Prentice, Yutaka Yasui, Kieran O'Doherty, Gloria M. Petersen, Cornelia M. Ulrich, Ilona Csizmadi, Ernest K. Amankwah, Nigel T. Brockton, Karen KopciukS. Elizabeth McGregor, Linda E. Kelemen

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Epidemiologic studies have adapted to the genomics era by forming large international consortia to overcome issues of large data volume and small sample size. Whereas both cohort and well-conducted case-control studies can inform disease risk from genetic susceptibility, cohort studies offer the additional advantages of assessing lifestyle and environmental exposure-disease time sequences often over a life course. Consortium involvement poses several logistical and ethical issues to investigators, some of which are unique to cohort studies, including the challenge to harmonize prospectively collected lifestyle and environmental exposures validly across individual studies. An open forum to discuss the opportunities and challenges of large-scale cohorts and their consortia was held in June 2009 in Banff, Canada, and is summarized in this report.

Original languageEnglish (US)
Pages (from-to)463-468
Number of pages6
JournalCancer Causes and Control
Volume22
Issue number3
DOIs
StatePublished - Mar 2011

Keywords

  • Biobanks
  • Cancer
  • Cohort studies
  • Consortia
  • Data harmonization
  • Ethics
  • Molecular epidemiology

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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