Cognitive performance and cardiovascular markers of hyperarousal in primary insomnia

Naima Covassin, Massimiliano de Zambotti, Michela Sarlo, Giuliano De Min Tona, Simone Sarasso, Luciano Stegagno

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

The purpose of the present study was to assess differences in cardiovascular activity and cognitive performance between insomniacs and good sleepers. Sixteen undergraduates participated in the study, eight insomniacs (age 22.9 ± 2.4) enrolled in accord with DSM-IV criteria for primary insomnia, and eight good sleepers (24.8 ± 2.7) were controls. The task employed, Stop Signal Task, assesses motor inhibition processes and was administered in two sessions, before and after a night of polysomnographic recording. During task performance, cardiovascular measures such as heart rate (HR), stroke volume (SV), cardiac output (CO), pre-ejection period (PEP) and left ventricular ejection time (LVET) were continuously recorded by means of impedance cardiography. Performance results showed prolonged Stop Signal Delay (SSD) in the morning in both groups and slower Stop Signal Reaction Time (SSRT) in insomniacs compared with good sleepers, while no effects were observed for performance accuracy. Analyses performed on cardiovascular parameters revealed higher HR and lower LVET values in the insomnia group as compared to healthy controls in the evening. PEP, an index inversely related to sympathetic beta-adrenergic activity, was continuously reduced in insomniacs, indicating constantly enhanced sympathetic activation. These findings suggest a deficit of motor inhibition control in insomnia, matched with high levels of cardiovascular arousal. Overall, our results support the notion that insomniacs suffer from both cognitive deficits and a hyperarousal disorder affecting somatic activity, that contribute to diurnal complaints often referred in addition to sleep disruption.

Original languageEnglish (US)
Pages (from-to)79-86
Number of pages8
JournalInternational Journal of Psychophysiology
Volume80
Issue number1
DOIs
StatePublished - Apr 1 2011

Keywords

  • Cardiovascular
  • Hyperarousal
  • Impedance cardiography
  • Motor inhibition
  • Primary insomnia
  • Stop signal task

ASJC Scopus subject areas

  • Neuroscience(all)
  • Neuropsychology and Physiological Psychology
  • Physiology (medical)

Fingerprint Dive into the research topics of 'Cognitive performance and cardiovascular markers of hyperarousal in primary insomnia'. Together they form a unique fingerprint.

  • Cite this