TY - JOUR
T1 - Cognitive impairment in Parkinson’s disease
T2 - a report from a multidisciplinary symposium on unmet needs and future directions to maintain cognitive health
AU - Goldman, Jennifer G.
AU - Vernaleo, Beth A.
AU - Camicioli, Richard
AU - Dahodwala, Nabila
AU - Dobkin, Roseanne D.
AU - Ellis, Terry
AU - Galvin, James E.
AU - Marras, Connie
AU - Edwards, Jerri
AU - Fields, Julie
AU - Golden, Robyn
AU - Karlawish, Jason
AU - Levin, Bonnie
AU - Shulman, Lisa
AU - Smith, Glenn
AU - Tangney, Christine
AU - Thomas, Cathi A.
AU - Tröster, Alexander I.
AU - Uc, Ergun Y.
AU - Coyan, Noreen
AU - Ellman, Crystal
AU - Ellman, Mike
AU - Hoffman, Charlie
AU - Hoffman, Susan
AU - Simmonds, Don
N1 - Publisher Copyright:
© 2018, The Author(s).
PY - 2018/12/1
Y1 - 2018/12/1
N2 - People with Parkinson’s disease (PD) and their care partners frequently report cognitive decline as one of their greatest concerns. Mild cognitive impairment affects approximately 20–50% of people with PD, and longitudinal studies reveal dementia in up to 80% of PD. Through the Parkinson’s Disease Foundation Community Choice Research Award Program, the PD community identified maintaining cognitive function as one of their major unmet needs. In response, a working group of experts across multiple disciplines was organized to evaluate the unmet needs, current challenges, and future opportunities related to cognitive impairment in PD. Specific conference goals included defining the current state in the field and gaps regarding cognitive issues in PD from patient, care partner, and healthcare professional viewpoints; discussing non-pharmacological interventions to help maintain cognitive function; forming recommendations for what people with PD can do at all disease stages to maintain cognitive health; and proposing ideas for how healthcare professionals can approach cognitive changes in PD. This paper summarizes the discussions of the conference, first by addressing what is currently known about cognitive dysfunction in PD and discussing several non-pharmacological interventions that are often suggested to people with PD. Second, based on the conference discussions, we provide considerations for people with PD for maintaining cognitive health and for healthcare professionals and care partners when working with people with PD experiencing cognitive impairment. Furthermore, we highlight key issues and knowledge gaps that need to be addressed in order to advance research in cognition in PD and improve clinical care.
AB - People with Parkinson’s disease (PD) and their care partners frequently report cognitive decline as one of their greatest concerns. Mild cognitive impairment affects approximately 20–50% of people with PD, and longitudinal studies reveal dementia in up to 80% of PD. Through the Parkinson’s Disease Foundation Community Choice Research Award Program, the PD community identified maintaining cognitive function as one of their major unmet needs. In response, a working group of experts across multiple disciplines was organized to evaluate the unmet needs, current challenges, and future opportunities related to cognitive impairment in PD. Specific conference goals included defining the current state in the field and gaps regarding cognitive issues in PD from patient, care partner, and healthcare professional viewpoints; discussing non-pharmacological interventions to help maintain cognitive function; forming recommendations for what people with PD can do at all disease stages to maintain cognitive health; and proposing ideas for how healthcare professionals can approach cognitive changes in PD. This paper summarizes the discussions of the conference, first by addressing what is currently known about cognitive dysfunction in PD and discussing several non-pharmacological interventions that are often suggested to people with PD. Second, based on the conference discussions, we provide considerations for people with PD for maintaining cognitive health and for healthcare professionals and care partners when working with people with PD experiencing cognitive impairment. Furthermore, we highlight key issues and knowledge gaps that need to be addressed in order to advance research in cognition in PD and improve clinical care.
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U2 - 10.1038/s41531-018-0055-3
DO - 10.1038/s41531-018-0055-3
M3 - Review article
AN - SCOPUS:85058860588
SN - 2373-8057
VL - 4
JO - npj Parkinson's Disease
JF - npj Parkinson's Disease
IS - 1
M1 - 19
ER -