Cognitive dysfunction after coronary artery bypass graft surgery

Dawn E. Jaroszewski, Lucas Restrepo

Research output: Contribution to journalArticle

Abstract

Coronary artery bypass graft surgery (CABG) is one of the most commonly performed major surgical procedures. However, patients having undergone CABG may experience neurological problems such as stroke, delirium, and cognitive difficulties. Observations suggest that these complications are caused by several synergistic factors, most prominently brain ischemia secondary to cerebral hypoperfusion and/or embolization of heterogeneous endovascular debris. Embolic signals are commonly detected during surgery using intraoperative transcranial Doppler monitoring. After surgery, magnetic resonance imaging of the brain may detect scattered areas of brain ischemia in patients with or without delirium. The large majority of these patients do not exhibit focal neurological deficits suggestive of ischemic stroke. We review the literature pertaining to postoperative encephalopathy, with emphasis on prevention, diagnosis, and treatment.

Original languageEnglish (US)
Pages (from-to)109-116
Number of pages8
JournalSeminars in Cerebrovascular Diseases and Stroke
Volume4
Issue number2 SPEC. ISS.
DOIs
StatePublished - Jun 2004

Keywords

  • Coronary artery bypass graft surgery
  • Dementia
  • Ischemic stroke
  • Postoperative encephalopathy
  • Vascular dementia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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