Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6

Katarina Bojanić, Wayne T. Nicholson, Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Abstract

This case discusses a pharmacokinetic interaction between the prodrug codeine and fluoxetine. Codeine is converted to its active metabolite morphine by cytochrome P450 2D6. Fluoxetine is a 2D6 inhibitor.

Original languageEnglish (US)
Title of host publicationA Case Approach to Perioperative Drug-Drug Interactions
PublisherSpringer New York
Pages269-273
Number of pages5
ISBN (Print)9781461474951, 9781461474944
DOIs
StatePublished - Sep 15 2015

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Codeine
Cytochrome P-450 CYP2D6
Fluoxetine
Prodrugs
Morphine
Pharmacokinetics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bojanić, K., Nicholson, W. T., Wittwer, E. D., Weingarten, T. N., & Sprung, J. (2015). Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 269-273). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_56

Codeine can't do it : Fatal forty DDI: Codeine, fluoxetine, CYP2D6. / Bojanić, Katarina; Nicholson, Wayne T.; Wittwer, Erica D.; Weingarten, Toby N.; Sprung, Juraj.

A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, 2015. p. 269-273.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bojanić, K, Nicholson, WT, Wittwer, ED, Weingarten, TN & Sprung, J 2015, Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6. in A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, pp. 269-273. https://doi.org/10.1007/978-1-4614-7495-1_56
Bojanić K, Nicholson WT, Wittwer ED, Weingarten TN, Sprung J. Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6. In A Case Approach to Perioperative Drug-Drug Interactions. Springer New York. 2015. p. 269-273 https://doi.org/10.1007/978-1-4614-7495-1_56
Bojanić, Katarina ; Nicholson, Wayne T. ; Wittwer, Erica D. ; Weingarten, Toby N. ; Sprung, Juraj. / Codeine can't do it : Fatal forty DDI: Codeine, fluoxetine, CYP2D6. A Case Approach to Perioperative Drug-Drug Interactions. Springer New York, 2015. pp. 269-273
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