Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6

Katarina Bojanić; Wayne T. Nicholson; Erica D. Wittwer; Toby N. Weingarten; Juraj Sprung

doi:10.1007/978-1-4614-7495-1_56

Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6

Katarina Bojanić, Wayne T. Nicholson, Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

1 Scopus citations

Abstract

This case discusses a pharmacokinetic interaction between the prodrug codeine and fluoxetine. Codeine is converted to its active metabolite morphine by cytochrome P450 2D6. Fluoxetine is a 2D6 inhibitor.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	269-273
Number of pages	5
ISBN (Electronic)	9781461474951
ISBN (Print)	9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_56
State	Published - Sep 15 2015

ASJC Scopus subject areas

General Medicine

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10.1007/978-1-4614-7495-1_56

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abstract = "This case discusses a pharmacokinetic interaction between the prodrug codeine and fluoxetine. Codeine is converted to its active metabolite morphine by cytochrome P450 2D6. Fluoxetine is a 2D6 inhibitor.",

author = "Katarina Bojani{\'c} and Nicholson, {Wayne T.} and Wittwer, {Erica D.} and Weingarten, {Toby N.} and Juraj Sprung",

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AU - Weingarten, Toby N.

AU - Sprung, Juraj

PY - 2015/9/15

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Codeine can't do it: Fatal forty DDI: Codeine, fluoxetine, CYP2D6

Abstract

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