TY - JOUR
T1 - Co-morbid sleep disorders and epilepsy
T2 - A narrative review and case examples
AU - Latreille, Veronique
AU - St. Louis, Erik K.
AU - Pavlova, Milena
N1 - Funding Information:
This work was supported by the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health , through Grant Number 1 UL1 RR024150-01 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The NIH had no involvement in the preparation of this article. We are additionally grateful for secretarial support in manuscript preparation, and proofreading from Ms. Lea Dacy, Mayo Clinic Department of Neurology.
Funding Information:
Dr. Latreille receives research support from the Canadian Institutes of Health Research (scholarship) and Biomobie Inc. Dr. St Louis receives research support from the National Institute on Aging and the National Heart, Lung and Blood Institute. Dr. Pavlova is supported by grants from Biomobie Inc and Lundbeck Inc.
PY - 2018/9
Y1 - 2018/9
N2 - Co-morbid sleep disorders, including sleep apnea, insomnia, restless legs syndrome, and the parasomnias, occur frequently in people with epilepsy. This article reviews the cardinal presenting symptoms and diagnostic features of each of these disorders to enable epileptologists to readily screen and identify sleep co-morbidities in their patients. It summarizes current evidence concerning the reciprocal relationship between sleep disturbances and epilepsy and available treatment options for common sleep disorders in people with epilepsy. Several illustrative cases demonstrate the practical consequences of co-morbid sleep disorders in epilepsy patients and suggest diagnostic and treatment approaches that may improve daytime functioning, alertness, quality of life, and seizure burden.
AB - Co-morbid sleep disorders, including sleep apnea, insomnia, restless legs syndrome, and the parasomnias, occur frequently in people with epilepsy. This article reviews the cardinal presenting symptoms and diagnostic features of each of these disorders to enable epileptologists to readily screen and identify sleep co-morbidities in their patients. It summarizes current evidence concerning the reciprocal relationship between sleep disturbances and epilepsy and available treatment options for common sleep disorders in people with epilepsy. Several illustrative cases demonstrate the practical consequences of co-morbid sleep disorders in epilepsy patients and suggest diagnostic and treatment approaches that may improve daytime functioning, alertness, quality of life, and seizure burden.
KW - Co-morbid sleep disorders
KW - Insomnia
KW - Parasomnias
KW - Restless legs syndrome
KW - Sleep apnea
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U2 - 10.1016/j.eplepsyres.2018.07.005
DO - 10.1016/j.eplepsyres.2018.07.005
M3 - Review article
C2 - 30048932
AN - SCOPUS:85050242961
VL - 145
SP - 185
EP - 197
JO - Journal of Epilepsy
JF - Journal of Epilepsy
SN - 0920-1211
ER -