Abstract
Human cytomegalovirus (CMV) is a leading congenital infectious agent in developed countries. In the past, the incidence of congenital infection has been rather low in Japan because a high seroprevalence of CMV present in young women. However, this seroprevalence has been decreasing in recent years, so that the incidence of congenital CMV infection in Japanese neonates may increase and approach the level seen in other developed countries. The method was used for detecting CMV DNA reported by Barbi et al. [Barbi et al. (1996): Clin Diagn Virol 6:27-32] using a dried blood spot on filter paper, to diagnose congenital CMV infection in Japanese neonates. This method is effective and less laborious than virus isolation both for epidemiological studies and for identifying asymptomatic infected babies. Japanese neonates (1,176) were examined; two of who were asymptomatic were found to be infected.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 923-925 |
| Number of pages | 3 |
| Journal | Journal of Medical Virology |
| Volume | 78 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 2006 |
| Externally published | Yes |
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Keywords
- Congenital cytomegarovirus infection
- Dried blood spot-asymptomatic infection
ASJC Scopus subject areas
- Virology
Cite this
CMV DNA detection in dried blood spots for diagnosing congenital CMV infection in Japan. / Yamagishi, Yoshiaki; Miyagawa, Hiromi; Wada, Kazuko; Matsumoto, Sayuri; Arahori, Hitomi; Tamura, Arihiro; Taniguchi, Hidetoshi; Kanekiyo, Takahisa; Sashihara, Junji; Yoda, Tomoko; Kitagawa, Mikiya; Ozono, Keiichi.
In: Journal of Medical Virology, Vol. 78, No. 7, 07.2006, p. 923-925.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - CMV DNA detection in dried blood spots for diagnosing congenital CMV infection in Japan
AU - Yamagishi, Yoshiaki
AU - Miyagawa, Hiromi
AU - Wada, Kazuko
AU - Matsumoto, Sayuri
AU - Arahori, Hitomi
AU - Tamura, Arihiro
AU - Taniguchi, Hidetoshi
AU - Kanekiyo, Takahisa
AU - Sashihara, Junji
AU - Yoda, Tomoko
AU - Kitagawa, Mikiya
AU - Ozono, Keiichi
PY - 2006/7
Y1 - 2006/7
N2 - Human cytomegalovirus (CMV) is a leading congenital infectious agent in developed countries. In the past, the incidence of congenital infection has been rather low in Japan because a high seroprevalence of CMV present in young women. However, this seroprevalence has been decreasing in recent years, so that the incidence of congenital CMV infection in Japanese neonates may increase and approach the level seen in other developed countries. The method was used for detecting CMV DNA reported by Barbi et al. [Barbi et al. (1996): Clin Diagn Virol 6:27-32] using a dried blood spot on filter paper, to diagnose congenital CMV infection in Japanese neonates. This method is effective and less laborious than virus isolation both for epidemiological studies and for identifying asymptomatic infected babies. Japanese neonates (1,176) were examined; two of who were asymptomatic were found to be infected.
AB - Human cytomegalovirus (CMV) is a leading congenital infectious agent in developed countries. In the past, the incidence of congenital infection has been rather low in Japan because a high seroprevalence of CMV present in young women. However, this seroprevalence has been decreasing in recent years, so that the incidence of congenital CMV infection in Japanese neonates may increase and approach the level seen in other developed countries. The method was used for detecting CMV DNA reported by Barbi et al. [Barbi et al. (1996): Clin Diagn Virol 6:27-32] using a dried blood spot on filter paper, to diagnose congenital CMV infection in Japanese neonates. This method is effective and less laborious than virus isolation both for epidemiological studies and for identifying asymptomatic infected babies. Japanese neonates (1,176) were examined; two of who were asymptomatic were found to be infected.
KW - Congenital cytomegarovirus infection
KW - Dried blood spot-asymptomatic infection
UR - http://www.scopus.com/inward/record.url?scp=33744960714&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33744960714&partnerID=8YFLogxK
U2 - 10.1002/jmv.20642
DO - 10.1002/jmv.20642
M3 - Article
C2 - 16721859
AN - SCOPUS:33744960714
VL - 78
SP - 923
EP - 925
JO - Journal of Medical Virology
JF - Journal of Medical Virology
SN - 0146-6615
IS - 7
ER -