Closed-loop artificial pancreas systems: Physiological input to enhance next-generation devices

Yogish C Kudva, Rickey E. Carter, Claudio Cobelli, Rita Basu, Ananda Basu

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

To provide an understanding of both the preclinical and clinical aspects of closed-loop artificial pancreas systems, we provide a discussion of this topic as part of this two-part Bench to Clinic narrative. Here, the Bench narrative provides an in-depth understanding of insulin-glucose-glucagon physiology in conditions that mimic the free-living situation to the extent possible in type 1 diabetes that will help refine and improve future closed-loop system algorithms. In the Clinic narrative, Doyle and colleagues compare and evaluate technology used in current closed-loop studies to gain further momentum toward outpatient trials and eventual approval for widespread use.

Original languageEnglish (US)
Pages (from-to)1184-1190
Number of pages7
JournalDiabetes Care
Volume37
Issue number5
DOIs
StatePublished - 2014

Fingerprint

Artificial Pancreas
Glucagon
Type 1 Diabetes Mellitus
Outpatients
Insulin
Technology
Glucose
Equipment and Supplies

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Advanced and Specialized Nursing

Cite this

Closed-loop artificial pancreas systems : Physiological input to enhance next-generation devices. / Kudva, Yogish C; Carter, Rickey E.; Cobelli, Claudio; Basu, Rita; Basu, Ananda.

In: Diabetes Care, Vol. 37, No. 5, 2014, p. 1184-1190.

Research output: Contribution to journalArticle

Kudva, Yogish C ; Carter, Rickey E. ; Cobelli, Claudio ; Basu, Rita ; Basu, Ananda. / Closed-loop artificial pancreas systems : Physiological input to enhance next-generation devices. In: Diabetes Care. 2014 ; Vol. 37, No. 5. pp. 1184-1190.
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