Clip and dip: Fatal forty DDI: Carbamazepine, felodipine, CYP3A4

David W. Barbara; Randall Flick; Juraj Sprung

doi:10.1007/978-1-4614-7495-1_174

Clip and dip: Fatal forty DDI: Carbamazepine, felodipine, CYP3A4

David W. Barbara, Randall Flick, Juraj Sprung

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

This case discusses the pharmacokinetic interaction between felodipine, carbamzapine, and phenytoin, resulting in decreased antihypertensive effi cacy. Felodipine is a cytochrome P450 3A4 substrate and carbamzepine and phenytoin are 3A4 inducers.

Original language	English (US)
Title of host publication	A Case Approach to Perioperative Drug-Drug Interactions
Publisher	Springer New York
Pages	775-778
Number of pages	4
ISBN (Print)	9781461474951, 9781461474944
DOIs	https://doi.org/10.1007/978-1-4614-7495-1_174
State	Published - Sep 15 2015

ASJC Scopus subject areas

Medicine(all)

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10.1007/978-1-4614-7495-1_174

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title = "Clip and dip: Fatal forty DDI: Carbamazepine, felodipine, CYP3A4",

abstract = "This case discusses the pharmacokinetic interaction between felodipine, carbamzapine, and phenytoin, resulting in decreased antihypertensive effi cacy. Felodipine is a cytochrome P450 3A4 substrate and carbamzepine and phenytoin are 3A4 inducers.",

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AB - This case discusses the pharmacokinetic interaction between felodipine, carbamzapine, and phenytoin, resulting in decreased antihypertensive effi cacy. Felodipine is a cytochrome P450 3A4 substrate and carbamzepine and phenytoin are 3A4 inducers.

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Clip and dip: Fatal forty DDI: Carbamazepine, felodipine, CYP3A4

Abstract

ASJC Scopus subject areas

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