Abstract
Summary. Prior studies have suggested that loss of plasma cell CD 5 6 expression in multiple myeloma defines a unique patient subset and that CD56 expression reliably discriminates between monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM). We conducted a study of 68 untreated patients with MM from a single institution to define the clinicopathological correlates of CD56 expression. We find CD56 expression in 55% of MM. Lack of CD56 expression does not define a unique clinicopathological or prognostic entity in MM. Strong CD 5 6 expression can also be found in MGUS and does not help to distinguish from MM.
Original language | English (US) |
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Pages (from-to) | 459-461 |
Number of pages | 3 |
Journal | British journal of haematology |
Volume | 90 |
Issue number | 2 |
DOIs | |
State | Published - Jun 1995 |
Keywords
- CD56
- expression
- multiple myeloma
ASJC Scopus subject areas
- Hematology