Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone.

Panayiotis J. Papagelopoulos, Evanthia Galanis, Pantelis Trantafyllidis, Peter J. Boscainos, Franklin H. Sim, K. Krishnan Unni

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Fibrosarcoma of bone is a relatively rare tumor; it accounts for less than 5% of bone sarcomas. The anatomical sites most commonly involved are the metaphyses of long tubular bones. Local pain, swelling, limitation of motion, and pathologic fracture are the common clinical signs and symptoms. Typical imaging findings include eccentrically located lytic lesions, with a geographic, moth-eaten, or permeative pattern of bone destruction, and extension into adjacent soft tissues. Surgery is the treatment of choice. The type of surgical procedure depends mainly on histologic grade, local conditions, and tumor location. With a high probability of metastases (>70%) after surgical treatment, perioperative adjuvant treatment modalities should be considered for high-grade tumors. The most important prognostic factors affecting survival include tumor grade, patient's age, and tumor location.

Original languageEnglish (US)
Pages (from-to)253-257
Number of pages5
JournalAmerican journal of orthopedics (Belle Mead, N.J.)
Volume31
Issue number5
StatePublished - May 2002
Externally publishedYes

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Fibrosarcoma
Bone and Bones
Neoplasms
Therapeutics
Spontaneous Fractures
Moths
Sarcoma
Signs and Symptoms
Neoplasm Metastasis
Pain
Survival

ASJC Scopus subject areas

  • Surgery

Cite this

Papagelopoulos, P. J., Galanis, E., Trantafyllidis, P., Boscainos, P. J., Sim, F. H., & Unni, K. K. (2002). Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone. American journal of orthopedics (Belle Mead, N.J.), 31(5), 253-257.

Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone. / Papagelopoulos, Panayiotis J.; Galanis, Evanthia; Trantafyllidis, Pantelis; Boscainos, Peter J.; Sim, Franklin H.; Unni, K. Krishnan.

In: American journal of orthopedics (Belle Mead, N.J.), Vol. 31, No. 5, 05.2002, p. 253-257.

Research output: Contribution to journalArticle

Papagelopoulos, PJ, Galanis, E, Trantafyllidis, P, Boscainos, PJ, Sim, FH & Unni, KK 2002, 'Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone.', American journal of orthopedics (Belle Mead, N.J.), vol. 31, no. 5, pp. 253-257.
Papagelopoulos PJ, Galanis E, Trantafyllidis P, Boscainos PJ, Sim FH, Unni KK. Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone. American journal of orthopedics (Belle Mead, N.J.). 2002 May;31(5):253-257.
Papagelopoulos, Panayiotis J. ; Galanis, Evanthia ; Trantafyllidis, Pantelis ; Boscainos, Peter J. ; Sim, Franklin H. ; Unni, K. Krishnan. / Clinicopathologic features, diagnosis, and treatment of fibrosarcoma of bone. In: American journal of orthopedics (Belle Mead, N.J.). 2002 ; Vol. 31, No. 5. pp. 253-257.
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