Abstract
Objective Supplement tomosynthesis-detected architectural distortions (AD) with CESM to better characterize malignant vs benign lesions. Methods Retrospective review CESM prior to biopsied AD. Pathology: benign, radial scar, or malignant. Results 49 lesions (45 patients). 29 invasive cancers, 1 DCIS (range, 0.4–4.7 cm); 9 radial scars; 10 benign. 37 (75.5%) ADs had associated enhancement. PPV 78.4% (29/37), sensitivity 96.7% (29/30); specificity, 57.9% (11/19); NPV, 91.7% (11/12). False-positive rate 21.6% (8/37); false-negative rate, 8.3% (1/12). Accuracy 81.6% (40/49). Conclusions High sensitivity and NPV of CESM in patients with AD is promising as an adjunct tool in diagnosing malignancy and avoiding unnecessary biopsy, respectively.
Original language | English (US) |
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Pages (from-to) | 44-52 |
Number of pages | 9 |
Journal | Clinical Imaging |
Volume | 46 |
DOIs | |
State | Published - Nov 2017 |
Keywords
- Architectural distortion
- Breast imaging
- CESM
- Contrast-enhanced spectral mammography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging