Clinical trials in brain tumor surgery

Jason M. Hoover; Susan M. Chang; Ian F. Parney

doi:10.1016/j.nic.2010.04.006

Clinical trials in brain tumor surgery

Jason M. Hoover, Susan M. Chang, Ian F. Parney

Neurosurgery

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

The prognosis for patients diagnosed with primary central nervous system tumors, such as gliomas, remains generally poor. Improved treatment (standard therapies and novel strategies) is needed. Glioma surgery is a key part of standard treatment and has established roles in providing tissue for diagnosis and in tumor debulking. Several techniques to increase safe surgical resection have been investigated. In addition, novel surgical modalities introducing therapeutic agents locally are increasingly common. This article reviews recent glioma surgery clinical trials, focusing on outcome studies, novel surgical techniques, and local therapeutic agent delivery.

Original language	English (US)
Pages (from-to)	409-424
Number of pages	16
Journal	Neuroimaging Clinics of North America
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/j.nic.2010.04.006
State	Published - Aug 2010

Keywords

Brain tumor
Central nervous system
Cytoreductive surgery
Gliomas

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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10.1016/j.nic.2010.04.006

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title = "Clinical trials in brain tumor surgery",

abstract = "The prognosis for patients diagnosed with primary central nervous system tumors, such as gliomas, remains generally poor. Improved treatment (standard therapies and novel strategies) is needed. Glioma surgery is a key part of standard treatment and has established roles in providing tissue for diagnosis and in tumor debulking. Several techniques to increase safe surgical resection have been investigated. In addition, novel surgical modalities introducing therapeutic agents locally are increasingly common. This article reviews recent glioma surgery clinical trials, focusing on outcome studies, novel surgical techniques, and local therapeutic agent delivery.",

keywords = "Brain tumor, Central nervous system, Cytoreductive surgery, Gliomas",

author = "Hoover, {Jason M.} and Chang, {Susan M.} and Parney, {Ian F.}",

year = "2010",

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T1 - Clinical trials in brain tumor surgery

AU - Hoover, Jason M.

AU - Chang, Susan M.

AU - Parney, Ian F.

PY - 2010/8

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N2 - The prognosis for patients diagnosed with primary central nervous system tumors, such as gliomas, remains generally poor. Improved treatment (standard therapies and novel strategies) is needed. Glioma surgery is a key part of standard treatment and has established roles in providing tissue for diagnosis and in tumor debulking. Several techniques to increase safe surgical resection have been investigated. In addition, novel surgical modalities introducing therapeutic agents locally are increasingly common. This article reviews recent glioma surgery clinical trials, focusing on outcome studies, novel surgical techniques, and local therapeutic agent delivery.

AB - The prognosis for patients diagnosed with primary central nervous system tumors, such as gliomas, remains generally poor. Improved treatment (standard therapies and novel strategies) is needed. Glioma surgery is a key part of standard treatment and has established roles in providing tissue for diagnosis and in tumor debulking. Several techniques to increase safe surgical resection have been investigated. In addition, novel surgical modalities introducing therapeutic agents locally are increasingly common. This article reviews recent glioma surgery clinical trials, focusing on outcome studies, novel surgical techniques, and local therapeutic agent delivery.

KW - Brain tumor

KW - Central nervous system

KW - Cytoreductive surgery

KW - Gliomas

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M3 - Review article

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JO - Neuroimaging Clinics of North America

JF - Neuroimaging Clinics of North America

IS - 3

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Clinical trials in brain tumor surgery

Abstract

Keywords

ASJC Scopus subject areas

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