TY - JOUR
T1 - Clinical spectrum of thunderclap headache
AU - Schwedt, Todd J.
N1 - Funding Information:
TJ Schwedt has no disclosures in regards to the topic presented herein. In the last 12 months, he has participitated in clinical trials supported by Allergan, GlaxoSmithKline and AGA Medical. He also receives funding from the National Institutes of Health.
PY - 2007/9
Y1 - 2007/9
N2 - Headaches of the thunderclap variety become severe in intensity within seconds to a minute of onset. Patients with thunderclap headache are to be evaluated in an emergent fashion as many of the underlying causes are associated with significant morbidity and mortality. Although subarachnoid hemorrhage is usually the initial consideration, a multitude of other etiologies have been identified and are discussed herein. In accordance with the increased utilization of cerebral imaging, availability of noninvasive techniques to image the cerebral vasculature and interest in identifying causes of thunderclap headaches, the list of potential causes is growing rapidly. Included in this growth are the reversible cerebral vasoconstriction syndromes, terminology recently introduced to unify several disorders all presenting with thunderclap headache and similar diagnostic findings including reversible vasoconstriction of the intracranial arteries.
AB - Headaches of the thunderclap variety become severe in intensity within seconds to a minute of onset. Patients with thunderclap headache are to be evaluated in an emergent fashion as many of the underlying causes are associated with significant morbidity and mortality. Although subarachnoid hemorrhage is usually the initial consideration, a multitude of other etiologies have been identified and are discussed herein. In accordance with the increased utilization of cerebral imaging, availability of noninvasive techniques to image the cerebral vasculature and interest in identifying causes of thunderclap headaches, the list of potential causes is growing rapidly. Included in this growth are the reversible cerebral vasoconstriction syndromes, terminology recently introduced to unify several disorders all presenting with thunderclap headache and similar diagnostic findings including reversible vasoconstriction of the intracranial arteries.
KW - Arterial dissection
KW - Intracranial aneurysm
KW - Intracranial hypotension
KW - Reversible cerebral vasoconstriction syndromes
KW - Sentinel headache
KW - Spontaneous cerebral venous sinus thrombosis
KW - Subarachnoid hemorrhage
KW - Thunderclap headache
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U2 - 10.1586/14737175.7.9.1135
DO - 10.1586/14737175.7.9.1135
M3 - Review article
C2 - 17868012
AN - SCOPUS:34548864399
SN - 1473-7175
VL - 7
SP - 1135
EP - 1144
JO - Expert review of neurotherapeutics
JF - Expert review of neurotherapeutics
IS - 9
ER -