Clinical manifestations of hemoglobin Chico at high altitude

Cindi R. Starkey, Lea Davies, James D. Hoyer, Carla S. Wilson, Stuart S. Winter

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Hemoglobin Chico is a rare hemoglobinopathy characterized by low oxygen affinity and a right-shifted oxygen dissociation curve. Detailed clinical evaluations of affected individuals have not been previously reported. We therefore report on the clinical features of Hemoglobin Chico in a Latino male living at high altitude, who desired to participate in school sports. As a young boy with asthma, he had the unusual finding of growth delay and digital clubbing which improved with asthma control. At 16 years of age, he had mild anemia and a decreased pulse oximetry (83%) but sufficient pulmonary reserve to participate in physically demanding activities.

Original languageEnglish (US)
Pages (from-to)760-762
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume28
Issue number11
DOIs
StatePublished - Nov 1 2006

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Keywords

  • Asthma
  • Digital clubbing
  • Hemoglobin Chico
  • Low-affinity hemoglobin

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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