Clinical guidelines for the management of pouchitis

Darrell S. Pardi, Geert D'Haens, Bo Shen, Simon Campbell, Paolo Gionchetti

Research output: Contribution to journalReview article

93 Scopus citations

Abstract

When surgery is necessary in patients with ulcerative colitis, total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the procedure of choice. Several inflammatory and noninflammatory complications can occur after IPAA. Pouchitis is the most common, occurring in ≈50% of patients. Whereas "acute" pouchitis can be treated rapidly and successfully in the majority of patients, "refractory" and "chronic pouchitis" remain therapeutic challenges to patients and physicians. This article reviews the literature and offers consensus guidelines on issues related to the epidemiology, diagnosis, pathogenesis, risk factors, and treatment of pouchitis.

Original languageEnglish (US)
Pages (from-to)1424-1431
Number of pages8
JournalInflammatory bowel diseases
Volume15
Issue number9
DOIs
StatePublished - Nov 26 2009

Keywords

  • Ileal pouch-anal anastomosis
  • Pouchitis
  • Ulcerative colitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Gastroenterology

Fingerprint Dive into the research topics of 'Clinical guidelines for the management of pouchitis'. Together they form a unique fingerprint.

  • Cite this

    Pardi, D. S., D'Haens, G., Shen, B., Campbell, S., & Gionchetti, P. (2009). Clinical guidelines for the management of pouchitis. Inflammatory bowel diseases, 15(9), 1424-1431. https://doi.org/10.1002/ibd.21039