It is crucial to delay the onset of dementia, one of the leading causes of mortality and morbidity in late-life for compelling reasons (see Chapters 2, 3, 7 and 15). If it were possible to delay the onset of dementia by about 2 years, the global prevalence of AD would decrease by 22.8 million cases. Eective prevention, as well as intervention, could dramatically reduce disease onset and progression. e identication of mild cognitive impairment (MCI) contributes to the early detection and prevention eort (Petersen et al., 1999b).
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