Clinical and pathological study of meningiomas of the first two decades of life

H. G. Deen, B. W. Scheithauer, M. J. Ebersold

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137 Scopus citations


The clinical features and pathological materials of 51 cases of histologically verified meningiomas in patients under 21 years of age were reviewed. The age range was 7 to 20 years, with the majority of cases being clustered in the second decade of life. There was virtually a 1:1 sex ratio, with 26 females and 25 males. Thirty-eight patients had intracranial meningiomas, three had intraorbital tumors, and 10 had intraspinal tumors. Twelve patients (24%) had neurofibromatosis. Twenty patients (39%) had tumor recurrence. The cases were subdivided into five histological categories: meningotheliomatous, fibrous, transitional, psammomatous, and papillary. In each case, the clinical course was correlated with histological subtype. The 15-year survival rate in patients with intracranial meningiomas of all types was 68%. Factors adversely affecting survival included infratentorial location, papillary histology, and evidence of brain invasion.

Original languageEnglish (US)
Pages (from-to)317-322
Number of pages6
JournalJournal of neurosurgery
Issue number3
StatePublished - Jan 1 1982

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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