Classification of normal and infarcted myocardium based on statistical analysis of high frequency intracardiac ultrasound RF signal

Research output: Contribution to journalConference article

1 Scopus citations

Abstract

Myocardial structural changes caused by infarction/reperfusion may result in increased scatterer density and variation of scatterer arrangement in ultrasound imaging. Homodyned K (HD_K) distribution is employed in this paper to model the backscattered signal from both normal and reperfused infarcted myocardium and is used to characterize them. Statistical testing showed that among the Rayleigh, K, Nakagami and Homodyned K distributions, the Homodyned K distribution is the best model to describe ultrasound signal backscattered from both normal and infarcted reperfused myocardium. Using HD_K distribution, in vivo demodulated RF data (8.5MHz) from anterior myocardial wall, as imaged from both left and right ventricle at baseline and after infarction/reperfusion, were analyzed. Significant increase of scatterer density in reperfused infarcted myocardium has been found compared to the normal myocardium. We concluded that HD_K distribution has potential to distinguish reperfused infarcted myocardium from normal using high frequency ultrasound imaging, irrespective of LV or RV data acquisition.

Original languageEnglish (US)
Pages (from-to)139-146
Number of pages8
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume4687
DOIs
StatePublished - Jan 1 2002
EventMedical Imaging 2002: Ultrasonic Imaging and Signal Processing - San Diego, CA, United States
Duration: Feb 26 2002Feb 28 2002

Keywords

  • Homodyned K distribution
  • Reperfused infarcted myocardiurm
  • Scatterer density
  • Ultrasound Backscatter Signal

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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