Ciliated adenocarcinoma of the ovary with evidence of serous differentiation: Report of a case

Andrew Peter Sciallis, Marie Christine Aubry, Debra A. Bell

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5 Scopus citations

Abstract

A patient with bilateral ovarian adenocarcinomas composed predominantly of ciliated cells incidentally found at autopsy is reported. Although obviously malignant, a majority of the cells expressed well-differentiated cilia with terminal bar formation. In one of the masses, the neoplastic cells seemed to arise from a serous adenofibroma. The tumor was confined to the ovaries without evidence of metastatic spread. Although morphologically resembling an endometrioid-type neoplasm, immunohistochemical and molecular studies were more consistent with a serous phenotype, especially in light of its apparent origination from a serous adenofibroma. We agree with previous observations suggesting that although the neoplasm seems morphologically worrisome, it may actually portend a more benign clinical course.

Original languageEnglish (US)
Pages (from-to)447-452
Number of pages6
JournalInternational Journal of Gynecological Pathology
Volume28
Issue number5
DOIs
StatePublished - Sep 1 2009

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Keywords

  • Cilia
  • Endometrioid
  • Ovarian ciliated adenocarcinoma
  • Serous adenofibroma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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