Chronic pancreatitis

Suresh T Chari, Eugene P. DiMagno

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

In the past year, there has been at least one important clinical paper that sheds light on the character and natural history of painful chronic pancreatitis, which has important clinical implications. In addition, several novel mutations have been described in the cationic trypsinogen gene in patients with hereditary pancreatitis. The mechanism by which these mutations cause pancreatic disease remains speculative. The diagnosis of early chronic pancreatitis is controversial. A novel noninvasive pancreatic function test (measurement of post-prandial APOB-48) was reported but is unlikely to be a sensitive test of pancreatic function. Pancreatic fibrosis is frequently seen in alcoholics without chronic pancreatitis, and this makes it difficult to interpret the findings on endoscopic ultrasonogram. Recent studies highlight the difficulty in abolishing pancreatic steatorrhea, Recently fibrosing colonopathy in adult patients has been reported. Extracorporeal shockwave lithotripsy combined with endoscopic therapy failed to benefit patients with calcific chronic pancreatitis.

Original languageEnglish (US)
Pages (from-to)414-418
Number of pages5
JournalCurrent Opinion in Gastroenterology
Volume16
Issue number5
DOIs
StatePublished - 2000

Fingerprint

Chronic Pancreatitis
Pancreatic Function Tests
Trypsinogen
Steatorrhea
Pancreatic Diseases
Mutation
Lithotripsy
Alcoholics
Meals
Fibrosis
Genes
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Chronic pancreatitis. / Chari, Suresh T; DiMagno, Eugene P.

In: Current Opinion in Gastroenterology, Vol. 16, No. 5, 2000, p. 414-418.

Research output: Contribution to journalArticle

Chari, Suresh T ; DiMagno, Eugene P. / Chronic pancreatitis. In: Current Opinion in Gastroenterology. 2000 ; Vol. 16, No. 5. pp. 414-418.
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