Chronic obstructive pulmonary disease after myocardial infarction in the community

Francesca Bursi, Robert Vassallo, Susan A. Weston, Jill M. Killian, Veronique Lee Roger

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Background: Myocardial infarction (MI) and chronic obstructive pulmonary disease (COPD) are frequent and share common risk factors. Yet, studies on MI patients reported limited and conflicting results on the prevalence of COPD, its impact on outcome, and how these may have changed over time. We examined, in a geographically defined community, the prevalence of COPD in patients with MI, its impact on mortality, and how these associations changed over time. Methods: Residents of Olmsted County, Minnesota, who experienced an MI meeting standardized criteria from 1979 to 2007 were included (3,438, 42% women, mean age 68 ± 15 years). Chronic obstructive pulmonary disease was ascertained from the medical records. Results: Of 3,438 patients, 415 (12%) had COPD. During the study, COPD prevalence increased from 7% in 1979-1985 to 15% in 2000-2007 (P < .001). Survival was worse in patients with COPD than in those without COPD (5-year survival rate: 46% [95% CI 41%-52%] vs 68% [95% CI 66%-70%], respectively; P < .01). The association between COPD and death was independent of age and risk factors (adjusted hazard ratio 1.30, 95% CI 1.10-1.54, P < .01) and did not change over time. Conclusions: In a large community of patients with MI, the prevalence of COPD increased over time and was associated with a markedly increased risk of death after MI independently of age, risk factors, and comorbidity. This underscores the importance of this condition and the need to optimize care for these high-risk patients.

Original languageEnglish (US)
Pages (from-to)95-101
Number of pages7
JournalAmerican Heart Journal
Volume160
Issue number1
DOIs
StatePublished - Jul 2010

Fingerprint

Chronic Obstructive Pulmonary Disease
Myocardial Infarction
Age Factors
Medical Records
Comorbidity
Survival Rate
Survival
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Chronic obstructive pulmonary disease after myocardial infarction in the community. / Bursi, Francesca; Vassallo, Robert; Weston, Susan A.; Killian, Jill M.; Roger, Veronique Lee.

In: American Heart Journal, Vol. 160, No. 1, 07.2010, p. 95-101.

Research output: Contribution to journalArticle

Bursi, Francesca ; Vassallo, Robert ; Weston, Susan A. ; Killian, Jill M. ; Roger, Veronique Lee. / Chronic obstructive pulmonary disease after myocardial infarction in the community. In: American Heart Journal. 2010 ; Vol. 160, No. 1. pp. 95-101.
@article{6137c0c0ec624cf1be25a1763693d92f,
title = "Chronic obstructive pulmonary disease after myocardial infarction in the community",
abstract = "Background: Myocardial infarction (MI) and chronic obstructive pulmonary disease (COPD) are frequent and share common risk factors. Yet, studies on MI patients reported limited and conflicting results on the prevalence of COPD, its impact on outcome, and how these may have changed over time. We examined, in a geographically defined community, the prevalence of COPD in patients with MI, its impact on mortality, and how these associations changed over time. Methods: Residents of Olmsted County, Minnesota, who experienced an MI meeting standardized criteria from 1979 to 2007 were included (3,438, 42{\%} women, mean age 68 ± 15 years). Chronic obstructive pulmonary disease was ascertained from the medical records. Results: Of 3,438 patients, 415 (12{\%}) had COPD. During the study, COPD prevalence increased from 7{\%} in 1979-1985 to 15{\%} in 2000-2007 (P < .001). Survival was worse in patients with COPD than in those without COPD (5-year survival rate: 46{\%} [95{\%} CI 41{\%}-52{\%}] vs 68{\%} [95{\%} CI 66{\%}-70{\%}], respectively; P < .01). The association between COPD and death was independent of age and risk factors (adjusted hazard ratio 1.30, 95{\%} CI 1.10-1.54, P < .01) and did not change over time. Conclusions: In a large community of patients with MI, the prevalence of COPD increased over time and was associated with a markedly increased risk of death after MI independently of age, risk factors, and comorbidity. This underscores the importance of this condition and the need to optimize care for these high-risk patients.",
author = "Francesca Bursi and Robert Vassallo and Weston, {Susan A.} and Killian, {Jill M.} and Roger, {Veronique Lee}",
year = "2010",
month = "7",
doi = "10.1016/j.ahj.2010.05.004",
language = "English (US)",
volume = "160",
pages = "95--101",
journal = "American Heart Journal",
issn = "0002-8703",
publisher = "Mosby Inc.",
number = "1",

}

TY - JOUR

T1 - Chronic obstructive pulmonary disease after myocardial infarction in the community

AU - Bursi, Francesca

AU - Vassallo, Robert

AU - Weston, Susan A.

AU - Killian, Jill M.

AU - Roger, Veronique Lee

PY - 2010/7

Y1 - 2010/7

N2 - Background: Myocardial infarction (MI) and chronic obstructive pulmonary disease (COPD) are frequent and share common risk factors. Yet, studies on MI patients reported limited and conflicting results on the prevalence of COPD, its impact on outcome, and how these may have changed over time. We examined, in a geographically defined community, the prevalence of COPD in patients with MI, its impact on mortality, and how these associations changed over time. Methods: Residents of Olmsted County, Minnesota, who experienced an MI meeting standardized criteria from 1979 to 2007 were included (3,438, 42% women, mean age 68 ± 15 years). Chronic obstructive pulmonary disease was ascertained from the medical records. Results: Of 3,438 patients, 415 (12%) had COPD. During the study, COPD prevalence increased from 7% in 1979-1985 to 15% in 2000-2007 (P < .001). Survival was worse in patients with COPD than in those without COPD (5-year survival rate: 46% [95% CI 41%-52%] vs 68% [95% CI 66%-70%], respectively; P < .01). The association between COPD and death was independent of age and risk factors (adjusted hazard ratio 1.30, 95% CI 1.10-1.54, P < .01) and did not change over time. Conclusions: In a large community of patients with MI, the prevalence of COPD increased over time and was associated with a markedly increased risk of death after MI independently of age, risk factors, and comorbidity. This underscores the importance of this condition and the need to optimize care for these high-risk patients.

AB - Background: Myocardial infarction (MI) and chronic obstructive pulmonary disease (COPD) are frequent and share common risk factors. Yet, studies on MI patients reported limited and conflicting results on the prevalence of COPD, its impact on outcome, and how these may have changed over time. We examined, in a geographically defined community, the prevalence of COPD in patients with MI, its impact on mortality, and how these associations changed over time. Methods: Residents of Olmsted County, Minnesota, who experienced an MI meeting standardized criteria from 1979 to 2007 were included (3,438, 42% women, mean age 68 ± 15 years). Chronic obstructive pulmonary disease was ascertained from the medical records. Results: Of 3,438 patients, 415 (12%) had COPD. During the study, COPD prevalence increased from 7% in 1979-1985 to 15% in 2000-2007 (P < .001). Survival was worse in patients with COPD than in those without COPD (5-year survival rate: 46% [95% CI 41%-52%] vs 68% [95% CI 66%-70%], respectively; P < .01). The association between COPD and death was independent of age and risk factors (adjusted hazard ratio 1.30, 95% CI 1.10-1.54, P < .01) and did not change over time. Conclusions: In a large community of patients with MI, the prevalence of COPD increased over time and was associated with a markedly increased risk of death after MI independently of age, risk factors, and comorbidity. This underscores the importance of this condition and the need to optimize care for these high-risk patients.

UR - http://www.scopus.com/inward/record.url?scp=77955687583&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955687583&partnerID=8YFLogxK

U2 - 10.1016/j.ahj.2010.05.004

DO - 10.1016/j.ahj.2010.05.004

M3 - Article

C2 - 20598978

AN - SCOPUS:77955687583

VL - 160

SP - 95

EP - 101

JO - American Heart Journal

JF - American Heart Journal

SN - 0002-8703

IS - 1

ER -