Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

Gheorghe Popa; Cristina Blag; Horatiu Olteanu

doi:10.1177/1093526616671047

Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

Gheorghe Popa, Cristina Blag, Horatiu Olteanu

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

Abstract

Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

Original language	English (US)
Pages (from-to)	58-62
Number of pages	5
Journal	Pediatric and Developmental Pathology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1177/1093526616671047
State	Published - Feb 2017

Keywords

BCR-ABL1
Chronic myelogenous leukemia
Cytogenetics
Flow cytometry
Lymphoblastic leukemia/lymphoma

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Pathology and Forensic Medicine

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10.1177/1093526616671047

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abstract = "Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.",

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AU - Blag, Cristina

AU - Olteanu, Horatiu

PY - 2017/2

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N2 - Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

AB - Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

KW - BCR-ABL1

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KW - Cytogenetics

KW - Flow cytometry

KW - Lymphoblastic leukemia/lymphoma

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Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

Abstract

Keywords

ASJC Scopus subject areas

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