Chronic Myelogenous Leukemia Presenting as a Secondary Malignancy After BCR-ABL1-negative B-lymphoblastic Leukemia/Lymphoma in a Pediatric Patient

Gheorghe Popa, Cristina Blag, Horatiu Olteanu

Research output: Contribution to journalArticle

Abstract

Chronic myelogenous leukemia, BCR-ABL1 positive (CML) is a rare myeloproliferative neoplasm in children and presents even less often as a secondary malignancy in the pediatric population. Below, we report a patient with Philadelphia-negative B-lymphoblastic leukemia/lymphoma, who developed CML several years after achieving complete remission, and summarize the existing literature on the clinical and pathologic features of CML as a secondary pediatric malignancy.

Original languageEnglish (US)
Pages (from-to)58-62
Number of pages5
JournalPediatric and Developmental Pathology
Volume20
Issue number1
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Keywords

  • BCR-ABL1
  • Chronic myelogenous leukemia
  • Cytogenetics
  • Flow cytometry
  • Lymphoblastic leukemia/lymphoma

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine

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