Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology

William G. Wierda; John C. Byrd; Jeremy S. Abramson; Syed F. Bilgrami; Greg Bociek; Danielle Brander; Jennifer Brown; Asher A. Chanan-Khan; Julio C. Chavez; Steve E. Coutre; Randall S. Davis; Christopher D. Fletcher; Brian Hill; Brad S. Kahl; Manali Kamdar; Lawrence D. Kaplan; Nadia Khan; Thomas J. Kipps; Megan S. Lim; Shuo Ma; Sami Malek; Anthony Mato; Claudio Mosse; Mazyar Shadman; Tanya Siddiqi; Deborah Stephens; Suchitra Sundaram; Nina Wagner; Mary Dwyer; Hema Sundar

doi:10.6004/jnccn.2020.0006

Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology

William G. Wierda, John C. Byrd, Jeremy S. Abramson, Syed F. Bilgrami, Greg Bociek, Danielle Brander, Jennifer Brown, Asher A. Chanan-Khan, Julio C. Chavez, Steve E. Coutre, Randall S. Davis, Christopher D. Fletcher, Brian Hill, Brad S. Kahl, Manali Kamdar, Lawrence D. Kaplan, Nadia Khan, Thomas J. Kipps, Megan S. Lim, Shuo MaSami Malek, Anthony Mato, Claudio Mosse, Mazyar Shadman, Tanya Siddiqi, Deborah Stephens, Suchitra Sundaram, Nina Wagner, Mary Dwyer, Hema Sundar

Hematology / Oncology / Cancer Center / Breast Clinic

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are characterized by a progressive accumulation of leukemic cells in the peripheral blood, bone marrow, and lymphoid tissues. Treatment of CLL/SLL has evolved significantly in recent years because of the improved understanding of the disease biology and the development of novel targeted therapies. In patients with indications for initiating treatment, the selection of treatment should be based on the disease stage, patient's age and overall fitness (performance status and comorbid conditions), and cytogenetic abnormalities. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with CLL/SLL.

Original language	English (US)
Pages (from-to)	185-217
Number of pages	33
Journal	Journal of the National Comprehensive Cancer Network : JNCCN
Volume	18
Issue number	2
DOIs	https://doi.org/10.6004/jnccn.2020.0006
State	Published - Feb 1 2020

ASJC Scopus subject areas

Oncology

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Wierda, W. G., Byrd, J. C., Abramson, J. S., Bilgrami, S. F., Bociek, G., Brander, D., Brown, J., Chanan-Khan, A. A., Chavez, J. C., Coutre, S. E., Davis, R. S., Fletcher, C. D., Hill, B., Kahl, B. S., Kamdar, M., Kaplan, L. D., Khan, N., Kipps, T. J., Lim, M. S., ... Sundar, H. (2020). Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN, 18(2), 185-217. https://doi.org/10.6004/jnccn.2020.0006

Wierda, WG, Byrd, JC, Abramson, JS, Bilgrami, SF, Bociek, G, Brander, D, Brown, J, Chanan-Khan, AA, Chavez, JC, Coutre, SE, Davis, RS, Fletcher, CD, Hill, B, Kahl, BS, Kamdar, M, Kaplan, LD, Khan, N, Kipps, TJ, Lim, MS, Ma, S, Malek, S, Mato, A, Mosse, C, Shadman, M, Siddiqi, T, Stephens, D, Sundaram, S, Wagner, N, Dwyer, M & Sundar, H 2020, 'Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology', Journal of the National Comprehensive Cancer Network : JNCCN, vol. 18, no. 2, pp. 185-217. https://doi.org/10.6004/jnccn.2020.0006

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title = "Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology",

abstract = "Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are characterized by a progressive accumulation of leukemic cells in the peripheral blood, bone marrow, and lymphoid tissues. Treatment of CLL/SLL has evolved significantly in recent years because of the improved understanding of the disease biology and the development of novel targeted therapies. In patients with indications for initiating treatment, the selection of treatment should be based on the disease stage, patient's age and overall fitness (performance status and comorbid conditions), and cytogenetic abnormalities. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with CLL/SLL.",

author = "Wierda, {William G.} and Byrd, {John C.} and Abramson, {Jeremy S.} and Bilgrami, {Syed F.} and Greg Bociek and Danielle Brander and Jennifer Brown and Chanan-Khan, {Asher A.} and Chavez, {Julio C.} and Coutre, {Steve E.} and Davis, {Randall S.} and Fletcher, {Christopher D.} and Brian Hill and Kahl, {Brad S.} and Manali Kamdar and Kaplan, {Lawrence D.} and Nadia Khan and Kipps, {Thomas J.} and Lim, {Megan S.} and Shuo Ma and Sami Malek and Anthony Mato and Claudio Mosse and Mazyar Shadman and Tanya Siddiqi and Deborah Stephens and Suchitra Sundaram and Nina Wagner and Mary Dwyer and Hema Sundar",

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doi = "10.6004/jnccn.2020.0006",

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AU - Abramson, Jeremy S.

AU - Bilgrami, Syed F.

AU - Bociek, Greg

AU - Brander, Danielle

AU - Brown, Jennifer

AU - Chanan-Khan, Asher A.

AU - Chavez, Julio C.

AU - Coutre, Steve E.

AU - Davis, Randall S.

AU - Fletcher, Christopher D.

AU - Hill, Brian

AU - Kahl, Brad S.

AU - Kamdar, Manali

AU - Kaplan, Lawrence D.

AU - Khan, Nadia

AU - Kipps, Thomas J.

AU - Lim, Megan S.

AU - Ma, Shuo

AU - Malek, Sami

AU - Mato, Anthony

AU - Mosse, Claudio

AU - Shadman, Mazyar

AU - Siddiqi, Tanya

AU - Stephens, Deborah

AU - Sundaram, Suchitra

AU - Wagner, Nina

AU - Dwyer, Mary

AU - Sundar, Hema

PY - 2020/2/1

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N2 - Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are characterized by a progressive accumulation of leukemic cells in the peripheral blood, bone marrow, and lymphoid tissues. Treatment of CLL/SLL has evolved significantly in recent years because of the improved understanding of the disease biology and the development of novel targeted therapies. In patients with indications for initiating treatment, the selection of treatment should be based on the disease stage, patient's age and overall fitness (performance status and comorbid conditions), and cytogenetic abnormalities. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with CLL/SLL.

AB - Chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) are characterized by a progressive accumulation of leukemic cells in the peripheral blood, bone marrow, and lymphoid tissues. Treatment of CLL/SLL has evolved significantly in recent years because of the improved understanding of the disease biology and the development of novel targeted therapies. In patients with indications for initiating treatment, the selection of treatment should be based on the disease stage, patient's age and overall fitness (performance status and comorbid conditions), and cytogenetic abnormalities. This manuscript discusses the recommendations outlined in the NCCN Guidelines for the diagnosis and management of patients with CLL/SLL.

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Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 4.2020, NCCN Clinical Practice Guidelines in Oncology

Abstract

ASJC Scopus subject areas

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