Chromosomes at Work

Organization of Chromosome Territories in the Interphase Nucleus

Andrew J. Fritz, A. Rasim Barutcu, Lori Martin-Buley, Andre J van Wijnen, Sayyed K. Zaidi, Anthony N. Imbalzano, Jane B. Lian, Janet L. Stein, Gary S. Stein

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The organization of interphase chromosomes in chromosome territories (CTs) was first proposed more than one hundred years ago. The introduction of increasingly sophisticated microscopic and molecular techniques, now provide complementary strategies for studying CTs in greater depth than ever before. Here we provide an overview of these strategies and how they are being used to elucidate CT interactions and the role of these dynamically regulated, nuclear-structure building blocks in directly supporting nuclear function in a physiologically responsive manner.

Original languageEnglish (US)
Pages (from-to)9-19
Number of pages11
JournalJournal of Cellular Biochemistry
Volume117
Issue number1
DOIs
StatePublished - Jan 1 2016

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Interphase
Chromosomes

Keywords

  • CTs
  • INTERPHASE
  • NUCLEUS

ASJC Scopus subject areas

  • Biochemistry
  • Cell Biology
  • Molecular Biology

Cite this

Fritz, A. J., Barutcu, A. R., Martin-Buley, L., van Wijnen, A. J., Zaidi, S. K., Imbalzano, A. N., ... Stein, G. S. (2016). Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus. Journal of Cellular Biochemistry, 117(1), 9-19. https://doi.org/10.1002/jcb.25280

Chromosomes at Work : Organization of Chromosome Territories in the Interphase Nucleus. / Fritz, Andrew J.; Barutcu, A. Rasim; Martin-Buley, Lori; van Wijnen, Andre J; Zaidi, Sayyed K.; Imbalzano, Anthony N.; Lian, Jane B.; Stein, Janet L.; Stein, Gary S.

In: Journal of Cellular Biochemistry, Vol. 117, No. 1, 01.01.2016, p. 9-19.

Research output: Contribution to journalArticle

Fritz, AJ, Barutcu, AR, Martin-Buley, L, van Wijnen, AJ, Zaidi, SK, Imbalzano, AN, Lian, JB, Stein, JL & Stein, GS 2016, 'Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus', Journal of Cellular Biochemistry, vol. 117, no. 1, pp. 9-19. https://doi.org/10.1002/jcb.25280
Fritz AJ, Barutcu AR, Martin-Buley L, van Wijnen AJ, Zaidi SK, Imbalzano AN et al. Chromosomes at Work: Organization of Chromosome Territories in the Interphase Nucleus. Journal of Cellular Biochemistry. 2016 Jan 1;117(1):9-19. https://doi.org/10.1002/jcb.25280
Fritz, Andrew J. ; Barutcu, A. Rasim ; Martin-Buley, Lori ; van Wijnen, Andre J ; Zaidi, Sayyed K. ; Imbalzano, Anthony N. ; Lian, Jane B. ; Stein, Janet L. ; Stein, Gary S. / Chromosomes at Work : Organization of Chromosome Territories in the Interphase Nucleus. In: Journal of Cellular Biochemistry. 2016 ; Vol. 117, No. 1. pp. 9-19.
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