Choosing a pediatric recipient for orthotopic liver transplantation

J. Jeffrey Malatack, Daniel J Schaid, Andrew H. Urbach, J. Carlton Gartner, Basil J. Zitelli, Howard Rockette, John Fischer, Thomas E. Starzl, Shunzaburo Iwatsuki, Byers W. Shaw

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

Between March 3, 1981, and June 1, 1984, 216 children were evaluated for orthotopic liver transplantation. Of the 216 patients, 117 (55%) had recelved at least one liver transplant by June 1, 1985. Fifty-five (25%) died before transplantation. The 117 patients who received transplants were grouped according to severity of disease and degree of general decompensation at the time of transplantation. The severity of a patient's medical condition with the possible exception of deep hepatic coma, did not predict outcome following orthotopic liver transplantation. Seventy variables were assessed at the time of the evaluation. Twenty-three of the 70 variables were found to have prognostic significance with regard to death from progressive liver disease before transplantation. These 23 variables were Incorporated into a multivariate model to provide a means of determining the relative risk of death among pediatric patients with end-stage liver disease. This information may allow more informed selection of candidates awaiting liver transplantation.

Original languageEnglish (US)
Pages (from-to)479-489
Number of pages11
JournalThe Journal of Pediatrics
Volume111
Issue number4
DOIs
StatePublished - 1987
Externally publishedYes

Fingerprint

Liver Transplantation
Pediatrics
Transplantation
Transplants
End Stage Liver Disease
Hepatic Encephalopathy
Liver Diseases
Liver

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Malatack, J. J., Schaid, D. J., Urbach, A. H., Gartner, J. C., Zitelli, B. J., Rockette, H., ... Shaw, B. W. (1987). Choosing a pediatric recipient for orthotopic liver transplantation. The Journal of Pediatrics, 111(4), 479-489. https://doi.org/10.1016/S0022-3476(87)80105-1

Choosing a pediatric recipient for orthotopic liver transplantation. / Malatack, J. Jeffrey; Schaid, Daniel J; Urbach, Andrew H.; Gartner, J. Carlton; Zitelli, Basil J.; Rockette, Howard; Fischer, John; Starzl, Thomas E.; Iwatsuki, Shunzaburo; Shaw, Byers W.

In: The Journal of Pediatrics, Vol. 111, No. 4, 1987, p. 479-489.

Research output: Contribution to journalArticle

Malatack, JJ, Schaid, DJ, Urbach, AH, Gartner, JC, Zitelli, BJ, Rockette, H, Fischer, J, Starzl, TE, Iwatsuki, S & Shaw, BW 1987, 'Choosing a pediatric recipient for orthotopic liver transplantation', The Journal of Pediatrics, vol. 111, no. 4, pp. 479-489. https://doi.org/10.1016/S0022-3476(87)80105-1
Malatack, J. Jeffrey ; Schaid, Daniel J ; Urbach, Andrew H. ; Gartner, J. Carlton ; Zitelli, Basil J. ; Rockette, Howard ; Fischer, John ; Starzl, Thomas E. ; Iwatsuki, Shunzaburo ; Shaw, Byers W. / Choosing a pediatric recipient for orthotopic liver transplantation. In: The Journal of Pediatrics. 1987 ; Vol. 111, No. 4. pp. 479-489.
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