Chondrosarcoma arising within a radiation-induced osteochondroma several years following childhood total body irradiation: Case report

Shuji Nagata, Robert K. Shen, Nadia N Laack, Carrie Y. Inwards, Doris E. Wenger, Kimberly K. Amrami

Research output: Contribution to journalArticle

3 Scopus citations


Malignant degeneration arising in radiation-induced osteochondromas is extremely rare. We report a case of a 34-year-old man with a chondrosarcoma arising from an osteochondroma of the left posterior eighth rib that developed following total body irradiation received as part of the conditioning regimen prior to bone marrow transplantation at age 8. To our knowledge, this is only the fourth reported case of a chondrosarcoma arising within a radiation-induced osteochondroma and the first case occurring following childhood total body irradiation.

Original languageEnglish (US)
Pages (from-to)1173-1177
Number of pages5
JournalSkeletal Radiology
Issue number8
StatePublished - Aug 2013



  • Chondrosarcoma
  • Osteochondroma
  • Radiation-induced
  • Total body irradiation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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