Chocolate as a cough suppressant: Rationale and justification for an upcoming clinical trial

Thorvardur R. Halfdanarson, Aminah Jatoi

Research output: Contribution to journalArticle

9 Scopus citations


Cough is a troubling symptom for many patients with cancer. Current cough suppressants can cause side effects and, at the same time, might not provide absolute cough palliation. Suprisingly, accumulating evience suggests that dark chocolate can carry antitussive effects. Although mechanisms remain unknown, it is thought that theobromine, a methylxanthine intrinsic to dark chocolate, might potentially suppress cough. To date, clinical trials with dark chocolate have not been undertaken. This article describes an upcoming trial to determine whether dark chocolate might serve as an antitussive in patients with cancer.

Original languageEnglish (US)
Pages (from-to)119-122
Number of pages4
JournalSupportive Cancer Therapy
Issue number2
StatePublished - Jan 2007



  • Antitussive agents
  • Bronchodilation
  • Chocuhaler
  • Placebo

ASJC Scopus subject areas

  • Oncology
  • Pharmacology
  • Cancer Research

Cite this