Utilizing radioimmunoelectrophoresis, Epstein-Barr virus nuclear antigens (EBNA) with molecular weights of 67, 000 and 70, 000 were detected in NC37 cells, while the Raji cell line contained an antigen with a molecular weight of 70, 000. Cell lines containing the B-95 strain of Epstein-Barr virus (EBV) expressed antigens with a molecular weight of 73, 000. Three different B-lymphocyte cell lines, established by infection with the B-95 virus, also exhibited 73, 000 molecular weight EBNA proteins. Cell lines containing the P3HR-1 strain of EBV demonstrated a single antigen with a molecular weight of 72, 000. The results indicate that the molecular weight of EBNA is determined by the strain of infecting virus.
- Epstein-Barr virus
- Epstein-Barr virus nuclear antigen
ASJC Scopus subject areas
- Infectious Diseases