Characteristics of breast cancer patients who refuse surgery

David J. Restrepo, Andrea Sisti, Daniel Boczar, Maria T. Huayllani, Jennifer Fishe, Emmanuel Gabriel, Sarah A McLaughlin, Sanjay P Bagaria, Aaron Spaulding, Brian D. Rinker, Antonio J. Forte

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Aim: This study describes the demographic, socioeconomic, and tumor-specific characteristics of patients who refuse breast cancer surgery. Materials and Methods: This is a retrospective study of breast cancer patients from 2004-2015 captured by the National Cancer Data Base. Demographic, socioeconomic, and tumor-specific predictors were compared between patients who refused breast cancer surgery versus those who agreed to surgery, using bivariate and multivariate models. Results: A total of 2,445,870 patients met the inclusion criteria. On multivariate analysis, black and Asian patients had higher odds of refusing surgical treatment compared to whites (OR=2.16, CI=2.05-2.28, p<0.001), (OR=1.58, CI=1.41-1.76, p<0.001), respectively. Moreover, patients with government insurance (OR=1.97, CI=1.86-2.09, p<0.001) and uninsured patients (OR=3.91, CI=3.50-4.36, p<0.001) were found to have higher odds of surgical treatment refusal when compared to patients with private insurance. Conclusion: Specific demographic and disease-specific characteristics are related to refusing potentially life-saving breast cancer surgery.

Original languageEnglish (US)
Pages (from-to)4941-4945
Number of pages5
JournalAnticancer Research
Issue number9
StatePublished - Jan 1 2019


  • Breast cancer
  • Surgery refusal

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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