TY - JOUR
T1 - Characterisation of cross-reactivity of virus neutralising antibodies induced by feline panleukopenia virus and canine parvoviruses
AU - Nakamura, K.
AU - Ikeda, Y.
AU - Miyazawa, T.
AU - Tohya, Y.
AU - Takahashi, E.
AU - Mochizuki, M.
N1 - Funding Information:
This study was supported in part by grants from the Ministry of Education, Science, Sports and Culture of Japan. K. Nakamura is supported by Research Fellowships from the Japanese Society for the Promotion of Science for Young Scientists.
PY - 2001
Y1 - 2001
N2 - It was recently reported that canine parvoviruses (CPV) had entered cat populations and induced disease in infected cats, while they had affected only dogs in the past. It is important to determine whether conventional feline panleukopenia virus (FPLV) vaccines protect against recent CPV infections. In this study, the cross-reactivity of virus-neutralising (VN) and haemagglutinin-inhibition (HI) antibodies in cats induced by FPLV and CPVS were examined. Lower cross-reactivities of VN and HI antibodies against each CPV strain were observed in cats experimentally inoculated with FPLV or vaccinated with an inactivated FPLV vaccine. In addition, we revealed the existence of a novel type of FPLV, which reacted weakly with antibodies induced by the conventional FPLV vaccine.
AB - It was recently reported that canine parvoviruses (CPV) had entered cat populations and induced disease in infected cats, while they had affected only dogs in the past. It is important to determine whether conventional feline panleukopenia virus (FPLV) vaccines protect against recent CPV infections. In this study, the cross-reactivity of virus-neutralising (VN) and haemagglutinin-inhibition (HI) antibodies in cats induced by FPLV and CPVS were examined. Lower cross-reactivities of VN and HI antibodies against each CPV strain were observed in cats experimentally inoculated with FPLV or vaccinated with an inactivated FPLV vaccine. In addition, we revealed the existence of a novel type of FPLV, which reacted weakly with antibodies induced by the conventional FPLV vaccine.
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U2 - 10.1053/rvsc.2001.0492
DO - 10.1053/rvsc.2001.0492
M3 - Article
C2 - 11798298
AN - SCOPUS:0035694951
SN - 0034-5288
VL - 71
SP - 219
EP - 222
JO - Research in Veterinary Science
JF - Research in Veterinary Science
IS - 3
ER -