Characterisation of cross-reactivity of virus neutralising antibodies induced by feline panleukopenia virus and canine parvoviruses

K. Nakamura, Y. Ikeda, T. Miyazawa, Y. Tohya, E. Takahashi, M. Mochizuki

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

It was recently reported that canine parvoviruses (CPV) had entered cat populations and induced disease in infected cats, while they had affected only dogs in the past. It is important to determine whether conventional feline panleukopenia virus (FPLV) vaccines protect against recent CPV infections. In this study, the cross-reactivity of virus-neutralising (VN) and haemagglutinin-inhibition (HI) antibodies in cats induced by FPLV and CPVS were examined. Lower cross-reactivities of VN and HI antibodies against each CPV strain were observed in cats experimentally inoculated with FPLV or vaccinated with an inactivated FPLV vaccine. In addition, we revealed the existence of a novel type of FPLV, which reacted weakly with antibodies induced by the conventional FPLV vaccine.

Original languageEnglish (US)
Pages (from-to)219-222
Number of pages4
JournalResearch in Veterinary Science
Volume71
Issue number3
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • veterinary(all)

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