Chapter 8 Atherogenic Lipoprotein Subprofiling

Allison A. Ellington, Iftikhar J. Kullo

Research output: Chapter in Book/Report/Conference proceedingChapter

9 Scopus citations

Abstract

Elevated levels of low-density lipoprotein (LDL) cholesterol are a major risk factor for coronary heart disease. However, a significant number of coronary events occur in individuals with "normal" serum LDL cholesterol levels. It has been proposed that coronary heart disease (CHD) risk stratification may be improved by evaluating LDL particle size and number and lipoprotein (a) [Lp(a)] levels in addition to LDL-associated cholesterol levels. This chapter includes a brief review of lipoprotein biology and presents an overview of the association between novel lipoprotein markers and CHD risk. We also discuss methodologies currently available for atherogenic lipid subprofiling.

Original languageEnglish (US)
Title of host publicationAdvances in Clinical Chemistry
EditorsGregory Makowski
Pages295-317
Number of pages23
DOIs
StatePublished - Oct 20 2008

Publication series

NameAdvances in Clinical Chemistry
Volume46
ISSN (Print)0065-2423

ASJC Scopus subject areas

  • Chemistry(all)
  • Clinical Biochemistry

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    Ellington, A. A., & Kullo, I. J. (2008). Chapter 8 Atherogenic Lipoprotein Subprofiling. In G. Makowski (Ed.), Advances in Clinical Chemistry (pp. 295-317). (Advances in Clinical Chemistry; Vol. 46). https://doi.org/10.1016/S0065-2423(08)00408-3