Changes in health-related quality of life 1 year following strabismus Surgery

Sarah R. Hatt; David A. Leske; Laura Liebermann; Jonathan M. Holmes

doi:10.1016/j.ajo.2011.10.001

Changes in health-related quality of life 1 year following strabismus Surgery

Sarah R. Hatt, David A. Leske, Laura Liebermann, Jonathan M. Holmes

Ophthalmology

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Purpose: To report changes in health-related quality of life (HRQOL) 1 year following strabismus surgery. Design: Retrospective cohort study. Methods: Seventy-three adults undergoing strabismus surgery in a single clinical practice completed the Adult Strabismus-20 (AS-20) HRQOL questionnaire preoperatively and at 6 weeks and 1 year postoperatively. All included adults were successfully aligned at 6 weeks postoperatively. Success was defined based on clinical criteria. Change in AS-20 psychosocial and function scores was evaluated as: 1) difference in scores between 6 weeks and 1 year postoperatively and 2) proportions exceeding previously published limits of agreement at 6 weeks and 1 year. Results: For patients successfully aligned at both 6 weeks and 1 year (n = 51), further improvement in median scores was seen from 6 weeks to 1 year for both the psychosocial scale (83.8 vs 93.8; P <.0001) and the function scale (72.5 vs 77.5; P =.007). Also, a greater proportion exceeded limits of agreement at 1 year than at 6 weeks (psychosocial: 48% vs 30%; P =.007, function: 67% vs 51%; P =.01). For patients who became partial success (n = 18) or failure (n = 4) at 1 year there was a numerical decrease in scores at 1 year. Conclusions: Adult strabismus patients who remain successfully aligned show continued improvement in both psychosocial and function scores from 6 weeks to 1 year postoperatively, indicating that improvement in HRQOL is long-lasting. Evaluation of HRQOL should be considered when reporting strabismus surgery outcomes in clinical trials, and may prove helpful in assessing outcomes in clinical practice.

Original language	English (US)
Pages (from-to)	614-619
Number of pages	6
Journal	American journal of ophthalmology
Volume	153
Issue number	4
DOIs	https://doi.org/10.1016/j.ajo.2011.10.001
State	Published - Apr 2012

ASJC Scopus subject areas

Ophthalmology

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10.1016/j.ajo.2011.10.001

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@article{cf1b7373116a4bdb8ccd763b29d14085,

title = "Changes in health-related quality of life 1 year following strabismus Surgery",

abstract = "Purpose: To report changes in health-related quality of life (HRQOL) 1 year following strabismus surgery. Design: Retrospective cohort study. Methods: Seventy-three adults undergoing strabismus surgery in a single clinical practice completed the Adult Strabismus-20 (AS-20) HRQOL questionnaire preoperatively and at 6 weeks and 1 year postoperatively. All included adults were successfully aligned at 6 weeks postoperatively. Success was defined based on clinical criteria. Change in AS-20 psychosocial and function scores was evaluated as: 1) difference in scores between 6 weeks and 1 year postoperatively and 2) proportions exceeding previously published limits of agreement at 6 weeks and 1 year. Results: For patients successfully aligned at both 6 weeks and 1 year (n = 51), further improvement in median scores was seen from 6 weeks to 1 year for both the psychosocial scale (83.8 vs 93.8; P <.0001) and the function scale (72.5 vs 77.5; P =.007). Also, a greater proportion exceeded limits of agreement at 1 year than at 6 weeks (psychosocial: 48% vs 30%; P =.007, function: 67% vs 51%; P =.01). For patients who became partial success (n = 18) or failure (n = 4) at 1 year there was a numerical decrease in scores at 1 year. Conclusions: Adult strabismus patients who remain successfully aligned show continued improvement in both psychosocial and function scores from 6 weeks to 1 year postoperatively, indicating that improvement in HRQOL is long-lasting. Evaluation of HRQOL should be considered when reporting strabismus surgery outcomes in clinical trials, and may prove helpful in assessing outcomes in clinical practice.",

author = "Hatt, {Sarah R.} and Leske, {David A.} and Laura Liebermann and Holmes, {Jonathan M.}",

note = "Funding Information: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. Publication of this article was supported by Grants EY015799 and EY018810 from the National Institutes of Health , Bethesda, Maryland (J.M.H.), Research to Prevent Blindness , New York, New York (J.M.H. as Olga Keith Weiss Scholar and an unrestricted grant to the Department of Ophthalmology, Mayo Clinic), and Mayo Foundation , Rochester, Minnesota. Involved in design and conduct of the study (S.R.H., L.L., D.A.L., J.M.H.); collection of data (S.R.H., L.L., J.M.H.); management, analysis, and interpretation of the data (S.R.H., D.A.L., L.L., J.M.H.); and preparation, review, and approval of the manuscript (S.R.H., D.A.L., L.L., J.M.H.). The Institutional Review Board/Ethics Committee, Mayo Clinic, Rochester, Minnesota, prospectively approved this study. All experiments and data collection were conducted in a manner compliant with the Health Insurance Portability and Accountability Act. Informed consent was obtained from all participants. All research procedures adhered to the tenets of the Declaration of Helsinki.",

year = "2012",

month = apr,

doi = "10.1016/j.ajo.2011.10.001",

language = "English (US)",

volume = "153",

pages = "614--619",

journal = "American journal of ophthalmology",

issn = "0002-9394",

publisher = "Elsevier USA",

number = "4",

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TY - JOUR

T1 - Changes in health-related quality of life 1 year following strabismus Surgery

AU - Hatt, Sarah R.

AU - Leske, David A.

AU - Liebermann, Laura

AU - Holmes, Jonathan M.

N1 - Funding Information: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported. Publication of this article was supported by Grants EY015799 and EY018810 from the National Institutes of Health , Bethesda, Maryland (J.M.H.), Research to Prevent Blindness , New York, New York (J.M.H. as Olga Keith Weiss Scholar and an unrestricted grant to the Department of Ophthalmology, Mayo Clinic), and Mayo Foundation , Rochester, Minnesota. Involved in design and conduct of the study (S.R.H., L.L., D.A.L., J.M.H.); collection of data (S.R.H., L.L., J.M.H.); management, analysis, and interpretation of the data (S.R.H., D.A.L., L.L., J.M.H.); and preparation, review, and approval of the manuscript (S.R.H., D.A.L., L.L., J.M.H.). The Institutional Review Board/Ethics Committee, Mayo Clinic, Rochester, Minnesota, prospectively approved this study. All experiments and data collection were conducted in a manner compliant with the Health Insurance Portability and Accountability Act. Informed consent was obtained from all participants. All research procedures adhered to the tenets of the Declaration of Helsinki.

PY - 2012/4

Y1 - 2012/4

N2 - Purpose: To report changes in health-related quality of life (HRQOL) 1 year following strabismus surgery. Design: Retrospective cohort study. Methods: Seventy-three adults undergoing strabismus surgery in a single clinical practice completed the Adult Strabismus-20 (AS-20) HRQOL questionnaire preoperatively and at 6 weeks and 1 year postoperatively. All included adults were successfully aligned at 6 weeks postoperatively. Success was defined based on clinical criteria. Change in AS-20 psychosocial and function scores was evaluated as: 1) difference in scores between 6 weeks and 1 year postoperatively and 2) proportions exceeding previously published limits of agreement at 6 weeks and 1 year. Results: For patients successfully aligned at both 6 weeks and 1 year (n = 51), further improvement in median scores was seen from 6 weeks to 1 year for both the psychosocial scale (83.8 vs 93.8; P <.0001) and the function scale (72.5 vs 77.5; P =.007). Also, a greater proportion exceeded limits of agreement at 1 year than at 6 weeks (psychosocial: 48% vs 30%; P =.007, function: 67% vs 51%; P =.01). For patients who became partial success (n = 18) or failure (n = 4) at 1 year there was a numerical decrease in scores at 1 year. Conclusions: Adult strabismus patients who remain successfully aligned show continued improvement in both psychosocial and function scores from 6 weeks to 1 year postoperatively, indicating that improvement in HRQOL is long-lasting. Evaluation of HRQOL should be considered when reporting strabismus surgery outcomes in clinical trials, and may prove helpful in assessing outcomes in clinical practice.

AB - Purpose: To report changes in health-related quality of life (HRQOL) 1 year following strabismus surgery. Design: Retrospective cohort study. Methods: Seventy-three adults undergoing strabismus surgery in a single clinical practice completed the Adult Strabismus-20 (AS-20) HRQOL questionnaire preoperatively and at 6 weeks and 1 year postoperatively. All included adults were successfully aligned at 6 weeks postoperatively. Success was defined based on clinical criteria. Change in AS-20 psychosocial and function scores was evaluated as: 1) difference in scores between 6 weeks and 1 year postoperatively and 2) proportions exceeding previously published limits of agreement at 6 weeks and 1 year. Results: For patients successfully aligned at both 6 weeks and 1 year (n = 51), further improvement in median scores was seen from 6 weeks to 1 year for both the psychosocial scale (83.8 vs 93.8; P <.0001) and the function scale (72.5 vs 77.5; P =.007). Also, a greater proportion exceeded limits of agreement at 1 year than at 6 weeks (psychosocial: 48% vs 30%; P =.007, function: 67% vs 51%; P =.01). For patients who became partial success (n = 18) or failure (n = 4) at 1 year there was a numerical decrease in scores at 1 year. Conclusions: Adult strabismus patients who remain successfully aligned show continued improvement in both psychosocial and function scores from 6 weeks to 1 year postoperatively, indicating that improvement in HRQOL is long-lasting. Evaluation of HRQOL should be considered when reporting strabismus surgery outcomes in clinical trials, and may prove helpful in assessing outcomes in clinical practice.

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JO - American journal of ophthalmology

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Changes in health-related quality of life 1 year following strabismus Surgery

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