Change in seizure threshold during electroconvulsive therapy

Max Fink, Georgios Petrides, Charles Kellner, Martina Mueller, Rebecca Knapp, Mustafa M. Husain, Keith Rasmussen, Teri Rummans, Kevin O'Connor

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The seizure threshold (ST) is a measure of the minimum electrical energy necessary to induce a grand mal seizure. Dose titration of the ST has been suggested to optimize stimulus dosing in electroconvulsive therapy (ECT). The change in ST with remission is examined in a large sample of unipolar depressed patients. Methods: In a study of continuation treatments after successful ECT, the ST was determined at the first treatment and again 1 week after remission using a conventional ST measurement protocol. Patients were treated with bilateral electrode placement at 150% above the measured ST. Results: In 80 subjects, the ST measured the same in 70%, increased in 21%, and decreased in 9% at remission. Conclusions: In a study of bilateral ECT, the ST did not rise conclusively with remission.

Original languageEnglish (US)
Pages (from-to)114-116
Number of pages3
JournalJournal of ECT
Volume24
Issue number2
DOIs
StatePublished - Jun 2008

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Electroconvulsive Therapy
Seizures
Electrodes

Keywords

  • Bilateral ECT
  • Major depression
  • Seizure threshold

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience (miscellaneous)

Cite this

Fink, M., Petrides, G., Kellner, C., Mueller, M., Knapp, R., Husain, M. M., ... O'Connor, K. (2008). Change in seizure threshold during electroconvulsive therapy. Journal of ECT, 24(2), 114-116. https://doi.org/10.1097/YCT.0b013e31815f65b9

Change in seizure threshold during electroconvulsive therapy. / Fink, Max; Petrides, Georgios; Kellner, Charles; Mueller, Martina; Knapp, Rebecca; Husain, Mustafa M.; Rasmussen, Keith; Rummans, Teri; O'Connor, Kevin.

In: Journal of ECT, Vol. 24, No. 2, 06.2008, p. 114-116.

Research output: Contribution to journalArticle

Fink, M, Petrides, G, Kellner, C, Mueller, M, Knapp, R, Husain, MM, Rasmussen, K, Rummans, T & O'Connor, K 2008, 'Change in seizure threshold during electroconvulsive therapy', Journal of ECT, vol. 24, no. 2, pp. 114-116. https://doi.org/10.1097/YCT.0b013e31815f65b9
Fink M, Petrides G, Kellner C, Mueller M, Knapp R, Husain MM et al. Change in seizure threshold during electroconvulsive therapy. Journal of ECT. 2008 Jun;24(2):114-116. https://doi.org/10.1097/YCT.0b013e31815f65b9
Fink, Max ; Petrides, Georgios ; Kellner, Charles ; Mueller, Martina ; Knapp, Rebecca ; Husain, Mustafa M. ; Rasmussen, Keith ; Rummans, Teri ; O'Connor, Kevin. / Change in seizure threshold during electroconvulsive therapy. In: Journal of ECT. 2008 ; Vol. 24, No. 2. pp. 114-116.
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