Abstract
The development of mechanical and bioprosthetic valvular prostheses have enhanced the survival and quality of life for countless patients. Despite the benefits provided by prosthetic valves, there are still significant limitations to those currently available. The goal biological valve tissue engineering strives to overcome is the limitations of the currently available prosthetic valves. This review will outline some of the past and present approaches that have been and are being taken in an attempt to create the ideal replacement valve. In addition, some of the challenges associated with this task will be highlighted.
Original language | English (US) |
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Pages (from-to) | 319-334 |
Number of pages | 16 |
Journal | Interventional Cardiology (London) |
Volume | 5 |
Issue number | 3 |
DOIs | |
State | Published - Jun 2013 |
Keywords
- aortic valve
- bioreactor
- decellularization
- heart valve
- pulmonic valve
- recellularization
- scaffold
- stem cell
- tissue engineering
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine