Challenges in the pharmacological management of nursing home residents with overactive bladder or urinary incontinence

Barbara J. Zarowitz, Carrie Allen, Terrence O'Shea, Eric George Tangalos, Todd Berner, Joseph G. Ouslander

Research output: Contribution to journalArticle

8 Scopus citations


Objectives To determine the proportion of nursing home (NH) residents (NHR) with overactive bladder (OAB) or urinary incontinence (UI) with potential pharmacodynamic contraindications to antimuscarinic treatment because of concomitant anticholinergic medications or acetylcholinesterase inhibitors (AChEIs) and nonpharmacological limitations to antimuscarinic treatment. Design Cross-sectional retrospective analysis. Setting U.S. skilled nursing facilities. Participants Nursing home residents with a diagnosis of OAB or UI. Measurements Linked and deidentified pharmacy claims and Minimum Data Set (MDS) 3.0 records (October 1, 2010 to September 30, 2012). Results Of NHRs, 71.3% received at least one anticholinergic medication. Medications that can cause or worsen UI were used commonly. AChEIs and antimuscarinic treatment were prescribed concurrently in 24% of NHRs with OAB or UI. NHRs with OAB or UI were more likely to have concurrent moderate to severe cognitive impairment (MSCI) (70.1%) than those without (29.9%) (P

Original languageEnglish (US)
Pages (from-to)2298-2307
Number of pages10
JournalJournal of the American Geriatrics Society
Issue number11
StatePublished - Nov 1 2015



  • nursing home
  • overactive bladder
  • urinary incontinence

ASJC Scopus subject areas

  • Geriatrics and Gerontology

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