Cerebrospinal Fluid Physiology and the Management of Increased Intracranial Pressure

MARK K. LYONS, FREDRIC B. MEYER

Research output: Contribution to journalReview article

69 Citations (Scopus)

Abstract

Increased intracranial pressure can result in irreversible injury to the central nervous system. Among the many functions of the cerebrospinal fluid, it provides protection against acute changes in venous and arterial blood pressure or impact pressure. Nevertheless, trauma, tumors, infections, neurosurgical procedures, and other factors can cause increased intracranial pressure. Both surgical and nonsurgical therapeutic modalities can be used in the management of increased intracranial pressure attributable to traumatic and nontraumatic causes. In patients with cerebral injury and increased intracranial pressure, monitoring of the intracranial pressure can provide an objective measure of the response to therapy and the pressure dynamics. Intraventricular, intraparenchymal, subarachnoid, and epidural sites can be used for monitoring, and the advantages and disadvantages of the various devices available are discussed. With the proper understanding of the physiologic features of the cerebrospinal fluid, the physician can apply the management principles reviewed herein to minimize damage from intracranial hypertension.

Original languageEnglish (US)
Pages (from-to)684-707
Number of pages24
JournalMayo Clinic Proceedings
Volume65
Issue number5
DOIs
StatePublished - 1990

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Intracranial Pressure
Cerebrospinal Fluid
Wounds and Injuries
Neurosurgical Procedures
Pressure
Venous Pressure
Intracranial Hypertension
Arterial Pressure
Central Nervous System
Physicians
Equipment and Supplies
Therapeutics
Infection
Neoplasms

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Cerebrospinal Fluid Physiology and the Management of Increased Intracranial Pressure. / LYONS, MARK K.; MEYER, FREDRIC B.

In: Mayo Clinic Proceedings, Vol. 65, No. 5, 1990, p. 684-707.

Research output: Contribution to journalReview article

LYONS, MARK K. ; MEYER, FREDRIC B. / Cerebrospinal Fluid Physiology and the Management of Increased Intracranial Pressure. In: Mayo Clinic Proceedings. 1990 ; Vol. 65, No. 5. pp. 684-707.
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