TY - JOUR
T1 - Cerebrospinal fluid-iophendylate contrast on gradient-echo MR images
AU - Jack, C. R.
AU - Gehring, D. G.
AU - Ehman, R. L.
AU - Felmlee, J. P.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - The effect on the signal intensities of cerebrospinal fluid (CSF) and iophendylate (Pantopaque) and on CSF-iophendylate contrast was studied in vitro with a small-nutation-angle (α) gradient refocused magnetic resonance (MR) imaging technique (GRASS) as α, repetition time (TR), and echo time (TE) were varied. CSF signal intensity was consistently greater than that of iophendylate. Therefore, retained intraspinal iophendylate may be considered in the differential diagnosis of focal areas of low signal intensity at the periphery of the spinal canal on GRASS images. At constant TE and TR, an increase in α from 6° to 45° increased the signal intensities of CSE and iophendylate but decreased CSF-iophendylate contrast. At constant α and TR, an increase in TE from 13 to 28 msec decreased the signal intensities of CSF and iophendylate but increased contrast. At constant α and TE, an increase in TR from 50 to 400 msec increased the signal intensities of CSF and iophendylate, as well as contrast. Clinical examples of the contrast behavior of retained intraspinal iophendylate on both spin-echo and GRASS images corroborate the experimental findings. Retained intraspinal iophendylate may mimic the appearance of intra- or extradural lesions, magnetic susceptibility artifact, and flow on gradient-echo MR images of the spine.
AB - The effect on the signal intensities of cerebrospinal fluid (CSF) and iophendylate (Pantopaque) and on CSF-iophendylate contrast was studied in vitro with a small-nutation-angle (α) gradient refocused magnetic resonance (MR) imaging technique (GRASS) as α, repetition time (TR), and echo time (TE) were varied. CSF signal intensity was consistently greater than that of iophendylate. Therefore, retained intraspinal iophendylate may be considered in the differential diagnosis of focal areas of low signal intensity at the periphery of the spinal canal on GRASS images. At constant TE and TR, an increase in α from 6° to 45° increased the signal intensities of CSE and iophendylate but decreased CSF-iophendylate contrast. At constant α and TR, an increase in TE from 13 to 28 msec decreased the signal intensities of CSF and iophendylate but increased contrast. At constant α and TE, an increase in TR from 50 to 400 msec increased the signal intensities of CSF and iophendylate, as well as contrast. Clinical examples of the contrast behavior of retained intraspinal iophendylate on both spin-echo and GRASS images corroborate the experimental findings. Retained intraspinal iophendylate may mimic the appearance of intra- or extradural lesions, magnetic susceptibility artifact, and flow on gradient-echo MR images of the spine.
UR - http://www.scopus.com/inward/record.url?scp=0023695094&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023695094&partnerID=8YFLogxK
U2 - 10.1148/radiology.169.2.3175007
DO - 10.1148/radiology.169.2.3175007
M3 - Article
C2 - 3175007
AN - SCOPUS:0023695094
VL - 169
SP - 561
EP - 563
JO - Radiology
JF - Radiology
SN - 0033-8419
IS - 2
ER -