Cerebral venous sinus thrombosis associated with essential thrombocytosis in a pediatric patient

Ashley W. Jensen; Ayalew Tefferi; Carola A.S. Arndt

doi:10.1097/MPH.0b013e3180377b9c

Cerebral venous sinus thrombosis associated with essential thrombocytosis in a pediatric patient

Ashley W. Jensen, Ayalew Tefferi, Carola A.S. Arndt

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Essential thrombocytosis (ET) is an uncommon pediatric hematologic disorder that can result in thrombotic complications, including cerebral venous sinus thrombosis (CVST). Although CVST associated with ET is exceedingly rare, it can be devastating to the patient. We here report a pediatric case of CVST associated with ET. The patient was treated with hydroxyurea and warfarin, which was later replaced by low-dose aspirin. Platelet counts were well controlled after 16 months of follow-up, and no further thrombotic events occurred. Mucositis was the main adverse effect of treatment.

Original language	English (US)
Pages (from-to)	156-159
Number of pages	4
Journal	Journal of Pediatric Hematology/Oncology
Volume	29
Issue number	3
DOIs	https://doi.org/10.1097/MPH.0b013e3180377b9c
State	Published - Mar 2007

Keywords

Essential thrombocytosis
Hydroxyurea
Venous sinus thrombosis

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1097/MPH.0b013e3180377b9c

Cite this

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abstract = "Essential thrombocytosis (ET) is an uncommon pediatric hematologic disorder that can result in thrombotic complications, including cerebral venous sinus thrombosis (CVST). Although CVST associated with ET is exceedingly rare, it can be devastating to the patient. We here report a pediatric case of CVST associated with ET. The patient was treated with hydroxyurea and warfarin, which was later replaced by low-dose aspirin. Platelet counts were well controlled after 16 months of follow-up, and no further thrombotic events occurred. Mucositis was the main adverse effect of treatment.",

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AB - Essential thrombocytosis (ET) is an uncommon pediatric hematologic disorder that can result in thrombotic complications, including cerebral venous sinus thrombosis (CVST). Although CVST associated with ET is exceedingly rare, it can be devastating to the patient. We here report a pediatric case of CVST associated with ET. The patient was treated with hydroxyurea and warfarin, which was later replaced by low-dose aspirin. Platelet counts were well controlled after 16 months of follow-up, and no further thrombotic events occurred. Mucositis was the main adverse effect of treatment.

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KW - Venous sinus thrombosis

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Cerebral venous sinus thrombosis associated with essential thrombocytosis in a pediatric patient

Abstract

Keywords

ASJC Scopus subject areas

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